Recombinant Human Cathepsin X/Z/P Protein, CF | R&D Systems 934-CY-010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Cathepsin X/Z/P Protein, CF

catalog :

934-CY-010

quantity :

10 ug

price :

456 USD

citations: 3

Reference
Bu x161 a M, Matou x161 kov xe1 Z, Barto x161 ov xe1 Sojkov xe1 P, Pachl P, x158 ez xe1 x10d ov xe1 P, Eichenberger R, et al. An evolutionary molecular adaptation of an unusual stefin from the liver fluke Fasciola hepatica redefines the cystatin superfamily. J Biol Chem. 2023;299:102970 pubmed publisher
Burster T, Marin Esteban V, Boehm B, Dunn S, Rotzschke O, Falk K, et al. Design of protease-resistant myelin basic protein-derived peptides by cleavage site directed amino acid substitutions. Biochem Pharmacol. 2007;74:1514-23 pubmed
Falgueyret J, Black W, Cromlish W, Desmarais S, Lamontagne S, Mellon C, et al. An activity-based probe for the determination of cysteine cathepsin protease activities in whole cells. Anal Biochem. 2004;335:218-27 pubmed

product information

master code :

934-CY

SKU :

934-CY-010

product name :

Recombinant Human Cathepsin X/Z/P Protein, CF

unit size :

10 ug

description :

The Recombinant Human Cathepsin X/Z/P Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Cathepsin X/Z/P Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Cathepsin X/Z/P

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Sodium Acetate and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

41 kDa, reducing conditions

theoretical molecular weight :

33 kDa

gene symbol :

CTSZ

details of functionality :

Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPPGFSAFK(Dnp)-OH (Catalog # ES005 ). The specific activity is 800 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q9UBR2

applications :

Enzyme Activity

source long :

Mouse myeloma cell line, NS0-derived human Cathepsin X/Z/P protein Ala21-Val303 (Gly23Val & Ser48Thr), with a C-terminal 10-His tag

source short :

NS0

USD :

456 USD

alt names :

Cathepsin P, Cathepsin Z, CTSX, CTSZ

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.