product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Hip Protein, CF
catalog :
9280-HP-050
quantity :
50 ug
price :
618 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Kathiriya J, Wang C, Zhou M, Brumwell A, Cassandras M, Le Saux C, et al. Human alveolar type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells. Nat Cell Biol. 2021;: pubmed publisher
Zhao X, Chang S, Liao M, Lo C, Chenier I, Luo H, et al. Hedgehog Interacting Protein Promotes Fibrosis and Apoptosis in Glomerular Endothelial Cells in Murine Diabetes. Sci Rep. 2018;8:5958 pubmed publisher
image
image 1 :
R&D Systems 9280-HP-050 image 1
Recombinant Human Hip Protein Bioactivity
product information
brand :
R&D Systems, a Bio-Techne brand
catalog number base :
9280-HP
SKU :
9280-HP-050
product name :
Recombinant Human Hip Protein, CF
description :
The Recombinant Human Hip Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Hip Protein, CF has been validated for the following applications: Bioactivity.
target :
Hip
unit size :
50 ug
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS and NaCl.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
observed molecular weight :
77-89 kDa, reducing conditions
theoretical molecular weight :
75 kDa
details of functionality :
Measured by its ability to inhibit Sonic Hedgehog (Shh) induction of alkaline phosphatase production in C3H10T1/2 mouse embryonic fibroblast cells. Recombinant Human Hip (Catalog # 9280-HP) inhibits a constant dose of 20 ng/mL of Recombinant Human Sonic Hedgehog/Shh Protein, High Activity (Catalog # 8908-SH ) in a C3H10T1/2 mouse embryonic fibroblast cell alkaline phosphatase induction assay with an ED50 = 0.1-0.6 µg/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q96QV1
applications :
Bioactivity
product keywords :
9280-HP, rhHip, hHip, carrier-free, carrier free, 928O-HP, 9280HP, Hedgehog
source :
CHO-derived Recombinant Human Hip Protein, CF
USD :
600
USD 2025 :
618 USD
alt names :
FLJ90230, hedgehog interacting protein, hedgehog-interacting protein, HHIP, HIPFLJ20992
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.