Recombinant Human GDF-15 (E. coli-expressed) Protein, CF | R&D Systems 9279-GD-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human GDF-15 (E. coli-expressed) Protein, CF

catalog :

9279-GD-050

quantity :

50 ug

price :

396 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
L xf6 sch L, Stemmler A, Fischer A, Steinmetz J, Schuldt L, Hennig C, et al. GDF15 Promotes the Osteogenic Cell Fate of Periodontal Ligament Fibroblasts, thus Affecting Their Mechanobiological Response. Int J Mol Sci. 2023;24: pubmed publisher
Wang S, Chang Y, Fang W, Li A, Chen C, Yeh T, et al. Growth differentiation factor 15 induces cisplatin resistance through upregulation of xCT expression and glutathione synthesis in gastric cancer. Cancer Sci. 2023;: pubmed publisher
Maschalidi S, Mehrotra P, Ke xe7 eli B, De Cleene H, Lecomte K, Van der Cruyssen R, et al. Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes. Nature. 2022;606:776-784 pubmed publisher

image

image 1 :

Recombinant Human GDF-15 (E. coli-expressed) Protein Bioactivity

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

9279-GD

SKU :

9279-GD-050

product name :

Recombinant Human GDF-15 (E. coli-expressed) Protein, CF

Description :

The Recombinant Human GDF-15 (E. coli-expressed) Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human GDF-15 (E. coli-expressed) Protein, CF has been validated for the following applications: Bioactivity.

target :

GDF-15

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in HCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

12 kDa, reducing conditions

theoretical molecular weight :

12 kDa

details of functionality :

Measured by its ability to activate SRE-SEAP reporter in HEK293 human embryonic kidney cells transfected with human c-Ret and human GFRAL. The ED50 for this effect is 0.2-2 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q99988

applications :

Bioactivity

source :

E. coli-derived Recombinant Human GDF-15 (E. coli-expressed) Protein

USD :

396 USD

alt names :

GDF15, growth differentiation factor 15, growth/differentiation factor 15, Macrophage inhibitory cytokine 1, MIC-1, MIC-1NSAID-activated gene 1 protein, MIC1Prostate differentiation factor, NAG-1, NAG-1NSAID-regulated gene 1 protein, NSAID (nonsteroidal inflammatory drug)-activated protein 1, PDF, PDFGDF-15, PLAB, PLABNRG-1, Placental bone morphogenetic protein, Placental TGF-beta, PTGF-beta, PTGFBPTGF-beta

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage