product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human CD19 Fc Chimera Protein, CF
catalog :
9269-CD-050
quantity :
50 ug
price :
503 USD
more info or order :
R&D Systems product webpage
citations: 4
Reference
Bolivar Wagers S, Loschi M, Jin S, Thangavelu G, Larson J, McDonald Hyman C, et al. Murine CAR19 Tregs suppress acute graft-versus-host disease and maintain graft-versus-tumor responses. JCI Insight. 2022;7: pubmed publisher
Wang X, Wong L, McElvain M, Martire S, Lee W, Li C, et al. A rational approach to assess off-target reactivity of a dual-signal integrator for T cell therapy. Toxicol Appl Pharmacol. 2022;437:115894 pubmed publisher
Mansilla Soto J, Eyquem J, Haubner S, Hamieh M, Feucht J, Paillon N, et al. HLA-independent T cell receptors for targeting tumors with low antigen density. Nat Med. 2022;28:345-352 pubmed publisher
Banihashemi S, Rahbarizadeh F, Zavaran Hosseini A, Ahmadvand D, Khoshtinat Nikkhoi S. Liposome-based nanocarriers loaded with anthrax lethal factor and armed with anti-CD19 VHH for effectively inhibiting MAPK pathway in B cells. Int Immunopharmacol. 2021;100:107927 pubmed publisher
image
image 1 :
R&D Systems 9269-CD-050 image 1
ELISA chart showing Recombinant Human CD19 binding to human CD81
product information
brand :
R&D Systems, a Bio-Techne brand
catalog number base :
9269-CD
SKU :
9269-CD-050
product name :
Recombinant Human CD19 Fc Chimera Protein, CF
description :
The Recombinant Human CD19 Fc Chimera Protein, CF from R&D Systems is derived from CHO. The Recombinant Human CD19 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
CD19
unit size :
50 ug
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
observed molecular weight :
77-92 kDa, reducing conditions
theoretical molecular weight :
57 kDa
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Human CD19 Fc Chimera is immobilized at 2 µg/mL,100 µL/well, recombinant biotinylated human CD81 Fc Chimera binds with an ED50 of 4-20 µg/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P15391
applications :
Bioactivity
product keywords :
9269-CD, rhCD19 Fc, hCD19, carrier-free, carrier free, 9269CD, B-lymphocyte antigen CD19, Leu 12, Leu12, B-lymphocyte antigen B4, hypogammaglobulinemia, follicular dendritic cells, T-Cell Surface Antigen Leu-12, Differentiation Antigen CD19, CVID3, B4
source :
CHO-derived Recombinant Human CD19 Fc Chimera Protein, CF
USD :
493
USD 2025 :
503 USD
alt names :
B4, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, CD19, CD19 antigen, CD19 molecule, CVID3, Differentiation antigen CD19, Leu-12, MGC12802, T-cell surface antigen Leu-12
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.