Recombinant Human S100A9 Protein, CF | R&D Systems 9254-S9-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human S100A9 Protein, CF

catalog :

9254-S9-050

quantity :

50 ug

price :

456 USD

citations: 7

Reference
Lim R, Thomas A, Ramasubramanian A, Chaurasia S. Retinal microglia-derived S100A9 incite NLRP3 inflammasome in a Western diet fed Ossabaw pig retina. bioRxiv. 2024;: pubmed publisher
Chen Q, Ishii K, Mori H, Nishijima A, Arai S, Miyazaki T, et al. Cryo-EM reveals structural basis for human AIM/CD5L recognition of polymeric immunoglobulin M. Nat Commun. 2024;15:9387 pubmed publisher
Henrioux F, Navel V, Belville C, Charnay C, Antoine A, Chiambaretta F, et al. Inflammation of Dry Eye Syndrome: A Cellular Study of the Epithelial and Macrophagic Involvement of NFAT5 and RAGE. Int J Mol Sci. 2023;24: pubmed publisher
Monteiro C, Miarka L, Perea García M, Priego N, García Gómez P, Álvaro Espinosa L, et al. Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism. Nat Med. 2022;28:752-765 pubmed publisher
Drosatos I, Tsoporis J, Izhar S, Gupta S, Tsirebolos G, Sakadakis E, et al. Differential Regulation of Circulating Soluble Receptor for Advanced Glycation End Products (sRAGEs) and Its Ligands S100A8/A9 Four Weeks Post an Exercise Intervention in a Cohort of Young Army Recruits. Biomolecules. 2021;11: pubmed publisher
Maehara N, Taniguchi K, Okuno A, Ando H, Hirota A, Li Z, et al. AIM/CD5L attenuates DAMPs in the injured brain and thereby ameliorates ischemic stroke. Cell Rep. 2021;36:109693 pubmed publisher
Lv Z, Li W, Wei X. S100A9 promotes prostate cancer cell invasion by activating TLR4/NF-κB/integrin β1/FAK signaling. Onco Targets Ther. 2020;13:6443-6452 pubmed publisher

product information

master code :

9254-S9

SKU :

9254-S9-050

product name :

Recombinant Human S100A9 Protein, CF

unit size :

50 ug

description :

The Recombinant Human S100A9 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human S100A9 Protein, CF has been validated for the following applications: Bioactivity.

target :

S100A9

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Tris, TCEP and Trehalose.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

12 kDa, reducing conditions

theoretical molecular weight :

13 kDa

details of functionality :

Measured by its ability to induce CXCL1/KC secretion by C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is 0.8-4 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Human S100A9 Protein Bioactivity

accessionNumbers :

P06702

applications :

Bioactivity

source long :

E. coli -derived human S100A9 protein Thr2-Pro114

source short :

E. coli

USD :

456 USD

alt names :

CAGBMigration inhibitory factor-related protein 14, calgranulin B, calgranulin-B, Calprotectin L1H subunit, CFAGMRP-14,60B8AG, CGLB, L1AG, LIAG, MAC387, MIF, MRP-14, MRP14Leukocyte L1 complex heavy chain, NIF, P14, protein S100-A9, S100 calcium binding protein A9, S100 calcium binding protein A9 (calgranulin B), S100 calcium-binding protein A9, S100 calcium-binding protein A9 (calgranulin B)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.