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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human S100A9 Protein, CF
catalog :
9254-S9-050
quantity :
50 ug
price :
417 USD
more info or order :
citations: 4
Reference
Monteiro C, Miarka L, Perea García M, Priego N, García Gómez P, Álvaro Espinosa L, et al. Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism. Nat Med. 2022;28:752-765 pubmed publisher
Drosatos I, Tsoporis J, Izhar S, Gupta S, Tsirebolos G, Sakadakis E, et al. Differential Regulation of Circulating Soluble Receptor for Advanced Glycation End Products (sRAGEs) and Its Ligands S100A8/A9 Four Weeks Post an Exercise Intervention in a Cohort of Young Army Recruits. Biomolecules. 2021;11: pubmed publisher
Maehara N, Taniguchi K, Okuno A, Ando H, Hirota A, Li Z, et al. AIM/CD5L attenuates DAMPs in the injured brain and thereby ameliorates ischemic stroke. Cell Rep. 2021;36:109693 pubmed publisher
Lv Z, Li W, Wei X. S100A9 promotes prostate cancer cell invasion by activating TLR4/NF-κB/integrin β1/FAK signaling. Onco Targets Ther. 2020;13:6443-6452 pubmed publisher
image
image 1 :
R&D Systems 9254-S9-050 image 1
Recombinant Human S100A9 Protein Bioactivity
product information
brand :
R&D Systems
master code :
9254-S9
SKU :
9254-S9-050
product name :
Recombinant Human S100A9 Protein, CF
description :
The Recombinant Human S100A9 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human S100A9 Protein, CF has been validated for the following applications: Bioactivity.
target :
S100A9
category :
Proteins and Enzymes
sizes available :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in Tris, TCEP and Trehalose.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
12 kDa, reducing conditions
theoretical molecular weight :
13 kDa
details of functionality :
Measured by its ability to induce CXCL1/KC secretion by C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is 0.8-4 µg/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P06702
applications :
Bioactivity
source :
E. coli-derived Recombinant Human S100A9 Protein, CF
USD :
410
USD 2023 :
417 USD
alt names :
CAGBMigration inhibitory factor-related protein 14, calgranulin B, calgranulin-B, Calprotectin L1H subunit, CFAGMRP-14,60B8AG, CGLB, L1AG, LIAG, MAC387, MIF, MRP-14, MRP14Leukocyte L1 complex heavy chain, NIF, P14, protein S100-A9, S100 calcium binding protein A9, S100 calcium binding protein A9 (calgranulin B), S100 calcium-binding protein A9, S100 calcium-binding protein A9 (calgranulin B)
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.