Recombinant Human IL-21R His-tag Protein, CF | R&D Systems 9249-R2-100 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IL-21R His-tag Protein, CF

catalog :

9249-R2-100

quantity :

100 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Chun J, Lim B, Roy S, Walsh M, Abhiraman G, Zhangxu K, et al. Potent antitumor activity of a designed interleukin-21 mimic. bioRxiv. 2024;: pubmed publisher
Ferreira Gomes M, Chen Y, Durek P, Rincón Arévalo H, Heinrich F, Bauer L, et al. Recruitment of plasma cells from IL-21-dependent and IL-21-independent immune reactions to the bone marrow. Nat Commun. 2024;15:4182 pubmed publisher

product information

master code :

9249-R2

SKU :

9249-R2-100

product name :

Recombinant Human IL-21R His-tag Protein, CF

unit size :

100 ug

description :

The Recombinant Human IL-21R His-tag Protein, CF from R&D Systems is derived from HEK293. The Recombinant Human IL-21R His-tag Protein, CF has been validated for the following applications: Bioactivity.

target :

IL-21R

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

45-53 kDa, reducing conditions

theoretical molecular weight :

26 kDa

details of functionality :

Measured by its ability to inhibit IL-21-dependent enhancement of IFN-gamma secretion in NK-92 human natural killer lymphoma cells. The ED50 for this effect is 15-150 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q9HBE5

applications :

Bioactivity

source long :

Human embryonic kidney cell, HEK293-derived human IL-21R protein Cys20-Pro236, with a C-terminal 6-His tag

source short :

HEK293

USD :

432 USD

alt names :

CD360, CD360 antigen, IL-21 R, IL-21 receptor, IL21R, IL-21R, interleukin 21 receptor, interleukin-21 receptor, MGC10967, NILR, Novel interleukin receptor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage