product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human IL-21R His-tag Protein, CF
catalog :
9249-R2-100
quantity :
100 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Chun J, Lim B, Roy S, Walsh M, Abhiraman G, Zhangxu K, et al. Potent antitumor activity of a designed interleukin-21 mimic. bioRxiv. 2024;: pubmed publisher
Ferreira Gomes M, Chen Y, Durek P, Rincón Arévalo H, Heinrich F, Bauer L, et al. Recruitment of plasma cells from IL-21-dependent and IL-21-independent immune reactions to the bone marrow. Nat Commun. 2024;15:4182 pubmed publisher
product information
brand :
R&D Systems
catalog number base :
9249-R2
SKU :
9249-R2-100
product name :
Recombinant Human IL-21R His-tag Protein, CF
units size :
100 ug
description :
The Recombinant Human IL-21R His-tag Protein, CF from R&D Systems is derived from HEK293. The Recombinant Human IL-21R His-tag Protein, CF has been validated for the following applications: Bioactivity.
target :
IL-21R
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
all_available conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
45-53 kDa, reducing conditions
theoretical molecular weight :
26 kDa
details of functionality :
Measured by its ability to inhibit IL-21-dependent enhancement of IFN-gamma secretion in NK-92 human natural killer lymphoma cells. The ED50 for this effect is 15-150 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q9HBE5
applications :
Bioactivity
source :
HEK293-derived Recombinant Human IL-21R His-tag Protein, CF
USD :
432 USD
alt names :
CD360, CD360 antigen, IL-21 R, IL-21 receptor, IL21R, IL-21R, interleukin 21 receptor, interleukin-21 receptor, MGC10967, NILR, Novel interleukin receptor
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.