This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Rat CTGF Protein, CF
catalog :
9237-CT-050
quantity :
50 ug
price :
503 USD
citations: 7
Reference
Shimizu M, Yoshimatsu G, Morita Y, Tanaka T, Sakata N, Tagashira H, et al. Rescue of murine hind limb ischemia via angiogenesis and lymphangiogenesis promoted by cellular communication network factor 2. Sci Rep. 2023;13:20029 pubmed publisher
Sun J, Zhang H, Liu D, Liu W, Du J, Wen D, et al. CTGF promotes the repair and regeneration of alveoli after acute lung injury by promoting the proliferation of subpopulation of AEC2s. Respir Res. 2023;24:227 pubmed publisher
Manieri E, Tie G, Seruggia D, Madha S, Maglieri A, Huang K, et al. Defining the structure, signals, and cellular elements of the gastric mesenchymal niche. bioRxiv. 2023;: pubmed publisher
Yuan Z, Wang J, Zhang H, Chai Y, Xu Y, Miao Y, et al. Glycocholic acid aggravates liver fibrosis by promoting the up-regulation of connective tissue growth factor in hepatocytes. Cell Signal. 2023;101:110508 pubmed publisher
Hashiguchi S, Tanaka T, Mano R, Kondo S, Kodama S. CCN2-induced lymphangiogenesis is mediated by the integrin αvβ5-ERK pathway and regulated by DUSP6. Sci Rep. 2022;12:926 pubmed publisher
Sun B, Lian M, Han Y, Mo X, Jiang W, Qiao Z, et al. A 3D-Bioprinted dual growth factor-releasing intervertebral disc scaffold induces nucleus pulposus and annulus fibrosus reconstruction. Bioact Mater. 2021;6:179-190 pubmed publisher
Hwang A, Nam J, Kang Y. Fluvastatin inhibits advanced glycation end products-induced proliferation, migration, and extracellular matrix accumulation in vascular smooth muscle cells by targeting connective tissue growth factor. Korean J Physiol Pharmacol. 2018;22:193-201 pubmed publisher
product information
master code :
9237-CT
SKU :
9237-CT-050
product name :
Recombinant Rat CTGF Protein, CF
unit size :
50 ug
description :
The Recombinant Rat CTGF Protein, CF from R&D Systems is derived from HEK293. The Recombinant Rat CTGF Protein, CF has been validated for the following applications: Bioactivity.
target :
CTGF/CCN2
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS and NaCl.
conjugate :
Unconjugated
purity :
>85%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Rat
observed molecular weight :
35-41 kDa, reducing conditions
theoretical molecular weight :
35 kDa
details of functionality :
Measured by its ability to mediate Balb/3T3 mouse embryonic fibroblast cell adhesion. Ball, D.K. etáal . (2003) Reproduction 125 :271. The ED50 for this effect is 1-5 ╡g/mL
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Rat CTGF Protein Bioactivity
accessionNumbers :
Q9R1E9
applications :
Bioactivity
source long :
Human embryonic kidney cell, HEK293-derived rat CTGF/CCN2 protein Gln25-Ala347
source short :
HEK293
USD :
503 USD
alt names :
CCN2, CCN2IGFBP-8, connective tissue growth factor, CTGRP, Fisp12, HCS24, Hypertrophic chondrocyte-specific protein 24, IBP-8, IGF-binding protein 8, IGFBP-8, IGFBP8CCN family member 2, Insulin-like growth factor-binding protein 8, MGC102839, NOV2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.