Recombinant Human VSIG3 Fc Chimera Protein, CF | R&D Systems 9229-VS-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human VSIG3 Fc Chimera Protein, CF

catalog :

9229-VS-050

quantity :

50 ug

price :

468 USD

citations: 2

Reference
Mehta N, Maddineni S, Mathews I, Andres Parra Sperberg R, Huang P, Cochran J. Structure and Functional Binding Epitope of V-domain Ig Suppressor of T Cell Activation. Cell Rep. 2019;28:2509-2516.e5 pubmed publisher
Wang J, Wu G, Manick B, Hernandez V, Renelt M, Erickson C, et al. VSIG-3 as a ligand of VISTA inhibits human T-cell function. Immunology. 2019;156:74-85 pubmed publisher

product information

master code :

9229-VS

SKU :

9229-VS-050

product name :

Recombinant Human VSIG3 Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Human VSIG3 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human VSIG3 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

VSIG3

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with trehalose.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

56-69 kDa, reducing conditions

theoretical molecular weight :

50 kDa

details of functionality :

Measured by its binding ability in a functional ELISA. Recombinant Human VSIG3 Fc Chimera (Catalog # 9229-VS) binds to Recombinant Human VISTA/B7-H5/PD-1H Fc Chimera (Catalog # 7126-B7) with an ED50 of 0.0750 - 0.750 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

BAC07546

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human VSIG3 protein Human VSIG3 (Leu23-Gly245) Accession # BAC07546 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

source short :

NS0

USD :

468 USD

alt names :

Brain and testis-specific immunoglobulin superfamily protein, Bt-IGSF, BTIGSF, cancer/testis antigen 119, CT119, CXADR like 1, CXADRL1, IgSF11, Igsf13, immunoglobulin superfamily member 11, immunoglobulin superfamily, member 11, MGC35227, V-set and immunoglobulin domain containing 3, V-set and immunoglobulin domain-containing protein 3, VSIG3brain and testis-specific immunoglobin superfamily protein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.