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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human 4-1BB/TNFRSF9 His-tag Protein, CF
catalog :
9220-4B-100
quantity :
100 ug
price :
400 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Geuijen C, Tacken P, Wang L, Klooster R, Van Loo P, Zhou J, et al. A human CD137×PD-L1 bispecific antibody promotes anti-tumor immunity via context-dependent T cell costimulation and checkpoint blockade. Nat Commun. 2021;12:4445 pubmed publisher
image
image 1 :
R&D Systems 9220-4B-100 image 1
Recombinant Human 4-1BB/TNFRSF9 His-tag Protein Bioactivity
product information
brand :
R&D Systems, a Bio-Techne brand
catalog number base :
9220-4B
SKU :
9220-4B-100
product name :
Recombinant Human 4-1BB/TNFRSF9 His-tag Protein, CF
description :
The Recombinant Human 4-1BB/TNFRSF9 His-tag Protein, CF from R&D Systems is derived from CHO. The Recombinant Human 4-1BB/TNFRSF9 His-tag Protein, CF has been validated for the following applications: Bioactivity.
target :
4-1BB/TNFRSF9/CD137
unit size :
100 ug
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
observed molecular weight :
25-38 kDa, reducing conditions
theoretical molecular weight :
18 kDa
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Human 4-1BB/TNFRSF9/CD137 is immobilized at 50 ng/mL, 100 µL/well, the concentration of Recombinant Human 4-1BB Ligand/TNFSF9 (Catalog # 2295-4L ) that produces 50% of the optimal binding response is approximately 2.5-12.5 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q07011
applications :
Bioactivity
product keywords :
9220-4B, rh4-1BB His-tag, h4-1BB, carrier-free, carrier free, 922O-4B, 92204B, immunechecktargets, 41BB, TNFRSF 9, 4 1BB, cytokine, cytokines,,s, TNFSFCoReg, TNFRSF Co-stimulatory
source :
CHO-derived Recombinant Human 4-1BB/TNFRSF9 His-tag Protein, CF
extended description :
Analyzed by SEC-MALS.
USD :
396
USD 2025 :
400 USD
product details :
Analyzed by SEC-MALS.
alt names :
41BB, 4-1BB, 4-1BB ligand receptor, CD137, CD137 antigen, CD137MGC2172, CDw137, FLJ43501, ILA, ILAhomolog of mouse 4-1BB, induced by lymphocyte activation (ILA), interleukin-activated receptor, homolog of mouse Ly63, receptor protein 4-1BB, T cell antigen ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, TNFRSF9, tumor necrosis factor receptor superfamily member 9, tumor necrosis factor receptor superfamily, member 9
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.