Recombinant Human EDA-A2 Protein | R&D Systems 922-ED-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human EDA-A2 Protein

catalog :

922-ED-010

quantity :

10 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Bilgic S, Domaniku A, Toledo B, Agca S, Weber B, Arabaci D, et al. EDA2R-NIK signalling promotes muscle atrophy linked to cancer cachexia. Nature. 2023;617:827-834 pubmed publisher
Clarke A, Poulton L, Shim D, Mabon D, Butt D, Pollard M, et al. An anti-TL1A antibody for the treatment of asthma and inflammatory bowel disease. MAbs. 2018;10:664-677 pubmed publisher
Brosh R, Sarig R, Natan E, Molchadsky A, Madar S, Bornstein C, et al. p53-dependent transcriptional regulation of EDA2R and its involvement in chemotherapy-induced hair loss. FEBS Lett. 2010;584:2473-7 pubmed publisher

product information

master code :

922-ED

SKU :

922-ED-010

product name :

Recombinant Human EDA-A2 Protein

unit size :

10 ug

description :

The Recombinant Human EDA-A2 Protein from R&D Systems is derived from NS0. The Recombinant Human EDA-A2 Protein has been validated for the following applications: Binding Activity.

target :

EDA-A2/Ectodysplasin A2

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

28-38 kDa, reducing conditions

theoretical molecular weight :

24.7 kDa

gene symbol :

EDA

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human EDA2R/TNFRSF27/XEDAR Fc Chimera (Catalog # 1093-XD ) is coated at 0.1 ╡g/mL (100 ╡L/well), the concentration of Recombinant Human EDA-A2/Ectodysplasin A2 that produces 50% of the optimal binding response is 3-15 ng/mL.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

AAC77371

applications :

Binding Activity

source long :

Mouse myeloma cell line, NS0-derived human EDA-A2/Ectodysplasin A2 protein MHHHHHHHHHH GGGSGGGSGGGS IEGR Human EDA-A2 (Ala179-Ser389) Accession # AAC77371 N-terminus C-terminus

source short :

NS0

USD :

432 USD

alt names :

ECTD1;Ectodysplasin-A;ED1;ED1-A1;ED1-A2;EDA1;EDA2;EDA-A1;EDA-A2;HED;HED1;ODT1;STHAGX1;TNLG7C;XHED;XLHED, EDAA2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage