Recombinant Human VEGF-C Protein | R&D Systems 9199-VC product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human VEGF-C Protein

catalog :

9199-VC

quantity :

25 ug

price :

329 USD

citations: 5

Reference
Geng X, Yanagida K, Akwii R, Choi D, Chen L, Ho Y, et al. S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling. JCI Insight. 2020;5: pubmed publisher
Chung T, Kim E, Choi H, Han C, Jang S, Kim K, et al. 6'-Sialylgalactose inhibits vascular endothelial growth factor receptor 2-mediated angiogenesis. Exp Mol Med. 2019;51:1-13 pubmed publisher
Frye M, Taddei A, Dierkes C, Martínez Corral I, Fielden M, Ortsäter H, et al. Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program. Nat Commun. 2018;9:1511 pubmed publisher
Lin Y, Ohbayashi N, Hongu T, Katagiri N, Funakoshi Y, Lee H, et al. Arf6 in lymphatic endothelial cells regulates lymphangiogenesis by controlling directional cell migration. Sci Rep. 2017;7:11431 pubmed publisher
Yu S, Lv H, Zhang H, Jiang Y, Hong Y, Xia R, et al. Heparanase-1-induced shedding of heparan sulfate from syndecan-1 in hepatocarcinoma cell facilitates lymphatic endothelial cell proliferation via VEGF-C/ERK pathway. Biochem Biophys Res Commun. 2017;485:432-439 pubmed publisher

product information

brand :

R&D Systems

master code :

9199-VC

SKU :

9199-VC-025

product name :

Recombinant Human VEGF-C Protein

description :

The Recombinant Human VEGF-C Protein from R&D Systems is derived from CHO. The Recombinant Human VEGF-C Protein has been validated for the following applications: Bioactivity.

target :

VEGF-C

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in HCl with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

13-20 kDa, reducing conditions

theoretical molecular weight :

13 kDa

details of functionality :

Measured in a cell proliferation assay using HMVEC human microvascular endothelial cells. Marconcini, L. et al . (1999) Proc. Natl. Acad. Sci. USA 96 :9671. The ED50 for this effect is 1.5-9 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

9199-VC

accessionNumbers :

P49767

applications :

Bioactivity

source :

Chinese Hamster Ovary cell line, CHO-derived human VEGF-C protein Ala112-Arg227

2020 USD :

329

2021 USD :

329 USD

alt names :

Flt4 ligand, Flt4-L, vascular endothelial growth factor C, Vascular endothelial growth factor-related protein, VEGFC, VEGF-C, VRPFLT4 ligand DHM

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.