product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human CD155/PVR Fc Chimera Protein, CF
catalog :
9174-CD-050
quantity :
50 ug (also 1 mg)
price :
434 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Preillon J, Cuende J, Rabolli V, Garnero L, Mercier M, Wald N, et al. Restoration of T-cell Effector Function, Depletion of Tregs, and Direct Killing of Tumor Cells: The Multiple Mechanisms of Action of a-TIGIT Antagonist Antibodies. Mol Cancer Ther. 2021;20:121-131 pubmed publisher
Fierle J, Abram Saliba J, Brioschi M, deTiani M, Coukos G, Dunn S. Integrating SpyCatcher/SpyTag covalent fusion technology into phage display workflows for rapid antibody discovery. Sci Rep. 2019;9:12815 pubmed publisher
Lucca L, Axisa P, Singer E, Nolan N, Dominguez Villar M, Hafler D. TIGIT signaling restores suppressor function of Th1 Tregs. JCI Insight. 2019;4: pubmed publisher
image
image 1 :
R&D Systems 9174-CD-050 image 1
Recombinant Human CD155/PVR Fc Chimera Protein Binding Activity
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
9174-CD
SKU :
9174-CD-050
product name :
Recombinant Human CD155/PVR Fc Chimera Protein, CF
Description :
The Recombinant Human CD155/PVR Fc Chimera Protein, CF from R&D Systems is derived from HEK293. The Recombinant Human CD155/PVR Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
CD155/PVR
category :
Proteins and Enzymes
unit size :
50 ug (also 1 mg)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
81-98 kDa, reducing conditions
theoretical molecular weight :
61 kDa
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Human CD155/PVR Fc Chimera is immobilized at 1 µg/mL (100 µL/well), the concentration of Recombinant Human CD96 v2 Fc Chimera (Catalog # 9556-CD ) that produces 50% of the optimal binding response is 30-150 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
NP_006496
applications :
Bioactivity
source :
HEK293-derived Recombinant Human CD155/PVR Fc Chimera Protein
extended description :
Analyzed by SEC-MALS
USD :
434 USD
product details :
Analyzed by SEC-MALS
alt names :
CD155, CD155 antigen, HVED, Necl-5, NECL5, nectin-like 5, Nectin-like protein 5, poliovirus receptor, PVR, PVS, PVSFLJ25946, Tage4
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.