Recombinant Human DPPIV/CD26 (High Purity Dimer) Protein, CF | R&D Systems 9168-SE-010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human DPPIV/CD26 (High Purity Dimer) Protein, CF

catalog :

9168-SE-010

quantity :

10 ug

price :

552 USD

citations: 11

Reference
Chen X, Shi Y, Huang Y, Ding M, Shen Q, Li C, et al. SDF-1 inhibits the dedifferentiation of islet β cells in hyperglycaemia by up-regulating FoxO1 via binding to CXCR4. J Cell Mol Med. 2022;26:750-763 pubmed publisher
Valverde A, Dunys J, Lorivel T, Debayle D, Gay A, Caillava C, et al. Dipeptidyl peptidase 4 contributes to Alzheimer's disease-like defects in a mouse model and is increased in sporadic Alzheimer's disease brains. J Biol Chem. 2021;297:100963 pubmed publisher
Gao H, Zhao Q, Tang S, Li K, Qin F, Song Z, et al. Continuous stimulation of dual-function peptide PGLP-1-VP inhibits the morbidity and mortality of NOD mice through anti-inflammation and immunoregulation. Sci Rep. 2021;11:3593 pubmed publisher
Cho J, Yang E, Quan W, Nam E, Cheon H. Discovery of a novel fibroblast activation protein (FAP) inhibitor, BR103354, with anti-diabetic and anti-steatotic effects. Sci Rep. 2020;10:21280 pubmed publisher
Tai W, He L, Zhang X, Pu J, Voronin D, Jiang S, et al. Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine. Cell Mol Immunol. 2020;17:613-620 pubmed publisher
Nishina S, Yamauchi A, Kawaguchi T, Kaku K, Goto M, Sasaki K, et al. Dipeptidyl Peptidase 4 Inhibitors Reduce Hepatocellular Carcinoma by Activating Lymphocyte Chemotaxis in Mice. Cell Mol Gastroenterol Hepatol. 2019;7:115-134 pubmed publisher
Gao H, Song Z, Zhao Q, Wu Y, Tang S, Alahdal M, et al. Pharmacological Effects of EGLP-1, a Novel Analog of Glucagon-Like Peptide-1, on Carbohydrate and Lipid Metabolism. Cell Physiol Biochem. 2018;48:1112-1122 pubmed publisher
Inn K, Kim Y, Aigerim A, Park U, Hwang E, Choi M, et al. Reduction of soluble dipeptidyl peptidase 4 levels in plasma of patients infected with Middle East respiratory syndrome coronavirus. Virology. 2018;518:324-327 pubmed publisher
Chen M, Lei X, Shi C, Huang M, Li X, Wu B, et al. Pericyte-targeting prodrug overcomes tumor resistance to vascular disrupting agents. J Clin Invest. 2017;127:3689-3701 pubmed publisher
Bromage D, Taferner S, Pillai M, Yellon D, Davidson S. A novel recombinant antibody specific to full-length stromal derived factor-1 for potential application in biomarker studies. PLoS ONE. 2017;12:e0174447 pubmed publisher
Willard J, Barrow B, Zraika S. Improved glycaemia in high-fat-fed neprilysin-deficient mice is associated with reduced DPP-4 activity and increased active GLP-1 levels. Diabetologia. 2017;60:701-708 pubmed publisher

product information

brand :

R&D Systems

MasterCode :

9168-SE

SKU :

9168-SE-010

product name :

Recombinant Human DPPIV/CD26 (High Purity Dimer) Protein, CF

Description :

The DPPIV/CD26 (High Purity Dimer) Protein from 9168-SE-010 is derived from NS0-derived Recombinant Human DPPIV/CD26 (High Purity Dimer) Protein, CF. The DPPIV/CD26 (High Purity Dimer) Protein has been validated for the following applications: CAA43118.

target :

DPPIV/CD26

category :

Proteins and Enzymes

unit size :

10 ug

buffer :

Supplied as a 0.2 µm filtered solution in MES and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

95-110 kDa, reducing condtions

theoretical molecular weight :

86 kDa

details of functionality :

Measured by its ability to cleave the fluorogenic peptide substrate, Gly-Pro-7-amido-4-methylcoumarin (GP-AMC). The specific activity is 8500 pmol/min/µg as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

CAA43118

applications :

Enzyme Activity

source :

NS0-derived Recombinant Human DPPIV/CD26 (High Purity Dimer) Protein, CF

USD :

552 USD

alt names :

ADABP, ADCP-2, ADCP2DPP IV, Adenosine deaminase complexing protein 2TP103, CD26, CD26 antigen, CD26T-cell activation antigen CD26, dipeptidyl peptidase 4, Dipeptidyl peptidase IV, dipeptidylpeptidase 4, dipeptidyl-peptidase 4, dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2), DPP4, DPPIV, EC 3.4.14.5

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.