product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Viral EBV IL-10 Protein
catalog :
915-VL-010
quantity :
10 ug
price :
447 USD
more info or order :
citations: 3
Reference
Stuchly J, Kanderová V, Vlkova M, Hermanova I, Slamova L, Pelak O, et al. Common Variable Immunodeficiency patients with a phenotypic profile of immunosenescence present with thrombocytopenia. Sci Rep. 2017;7:39710 pubmed publisher
Forster S, Brandt M, Mottok D, Zschüttig A, Zimmermann K, Blattner F, et al. Secretory expression of biologically active human Herpes virus interleukin-10 analogues in Escherichia coli via a modified Sec-dependent transporter construct. BMC Biotechnol. 2013;13:82 pubmed publisher
Chang W, Baumgarth N, Yu D, Barry P. Human cytomegalovirus-encoded interleukin-10 homolog inhibits maturation of dendritic cells and alters their functionality. J Virol. 2004;78:8720-31 pubmed
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
915-VL
SKU :
915-VL-010
product name :
Recombinant Viral EBV IL-10 Protein
Description :
The Recombinant Viral EBV IL-10 Protein from R&D Systems is derived from E. coli. The Recombinant Viral EBV IL-10 Protein has been validated for the following applications: Bioactivity.
target :
IL-10
category :
Proteins and Enzymes
unit size :
10 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in Tris and NaCl with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Viral
theoretical molecular weight :
17.2 kDa
gene symbol :
CeHV15gBCRF1
details of functionality :
Measured in a cell proliferation assay using MC/9-2 mouse mast cells. Thompson-Snipes, L.  et al . (1991) J. Exp. Med. 173 :507. The ED50 for this effect is 3-15 ng/mL.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P03180
applications :
Bioactivity
source :
E. coli-derived Recombinant Viral EBV IL-10 Protein
USD :
447 USD
alt names :
CSIF, CSIFMGC126450, Cytokine synthesis inhibitory factor, GVHDS, IL10, IL10A, IL-10MGC126451, interleukin 10, interleukin-10, TGIF
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.