product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Rat GITR/TNFRSF18 Fc Chimera Protein, CF
catalog :
9130-GR-050
quantity :
50 ug
price :
551 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
He Y, Pei Y, Liu K, Liu L, Tian Y, Li H, et al. GITR/GITRL reverse signalling modulates the proliferation of hepatic progenitor cells by recruiting ANXA2 to phosphorylate ERK1/2 and Akt. Cell Death Dis. 2022;13:297 pubmed publisher
product information
master code :
9130-GR
SKU :
9130-GR-050
product name :
Recombinant Rat GITR/TNFRSF18 Fc Chimera Protein, CF
unit size :
50 ug
description :
The Recombinant Rat GITR/TNFRSF18 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Rat GITR/TNFRSF18 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
GITR/TNFRSF18
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Rat
observed molecular weight :
55-64 kDa, reducing conditions
theoretical molecular weight :
41 kDa
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Rat GITR/TNFRSF18 Fc Chimera is immobilized at 2 ╡g/mL, 100 ╡L/well, the concentration of Recombinant Mouse GITR Ligand/TNFSF18 aa 47-173 (Catalog # 2177-GL ) that produces 50% of the optimal binding response is 25-150 ng/mL
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Rat GITR/TNFRSF18 Fc Chimera Protein Binding Activity
accessionNumbers :
NP_001019520
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived rat GITR/TNFRSF18 protein Rat GITR/TNFRSF18 (Glu25-His153) Accession # NP_001019520 IEGRMDP Mouse IgG2a (Glu98-Lys330) N-terminus C-terminus
source short :
NS0
USD :
551 USD
alt names :
Activation-inducible TNFR family receptor, AITR, AITRTNF receptor superfamily activation-inducible protein, CD357, CD357 antigen, GITR-D, GITRtumor necrosis factor receptor superfamily member 18, Glucocorticoid-induced TNFR-related protein, TNFRSF18, tumor necrosis factor receptor superfamily, member 18
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.