Recombinant Porcine IL-12 Protein | R&D Systems 912-PL product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Porcine IL-12 Protein

catalog :

912-PL

quantity :

25 ug

price :

379 USD

citations: 5

Reference
Elahi S, Thompson D, Van Kessel J, Babiuk L, Gerdts V. Protective Role of Passively Transferred Maternal Cytokines against Bordetella pertussis Infection in Newborn Piglets. Infect Immun. 2017;85: pubmed publisher
Mair K, Müllebner A, Essler S, Duvigneau J, Storset A, Saalmuller A, et al. Porcine CD8?dim/-NKp46high NK cells are in a highly activated state. Vet Res. 2013;44:13 pubmed publisher
Mair K, Essler S, Patzl M, Storset A, Saalmuller A, Gerner W. NKp46 expression discriminates porcine NK cells with different functional properties. Eur J Immunol. 2012;42:1261-71 pubmed publisher
Toka F, Nfon C, Dawson H, Estes D, Golde W. Activation of porcine natural killer cells and lysis of foot-and-mouth disease virus infected cells. J Interferon Cytokine Res. 2009;29:179-92 pubmed publisher
Azevedo M, Yuan L, Pouly S, Gonzales A, Jeong K, Nguyen T, et al. Cytokine responses in gnotobiotic pigs after infection with virulent or attenuated human rotavirus. J Virol. 2006;80:372-82 pubmed

product information

brand :

R&D Systems

master code :

912-PL

SKU :

912-PL-025

product name :

Recombinant Porcine IL-12 Protein

description :

The Recombinant Porcine IL-12 Protein from R&D Systems is derived from CHO. The Recombinant Porcine IL-12 Protein has been validated for the following applications: Bioactivity.

target :

IL-12

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Porcine

observed molecular weight :

60-70 kDa, non-reducing conditions

details of functionality :

Measured in a cell proliferation assay using PHA-stimulated human T lymphoblasts. Symons, J.A. et al . (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. et al . (eds): IRL Press. 272. The ED50 for this effect is 0.05-0.15 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

912-PL

accessionNumbers :

Q28938 (p40) Q29053 (p35)

applications :

Bioactivity

source :

Chinese Hamster Ovary cell line, CHO-derived porcine IL-12 protein Porcine IL-12 p40 (Ile23 - Asn324) Accession # Q28938 Porcine IL-12 p35 (Arg26 - Ser222) Accession # Q29053 N-terminus C-terminus

2020 USD :

379

2021 USD :

379 USD

alt names :

CLMF p35, CLMF1, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL12, IL-12 subunit p35, IL-12, subunit p35, IL12A, interleukin 12, p35, interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocytematuration factor 1, p35), interleukin-12 alpha chain, interleukin-12 subunit alpha, natural killer cell stimulatory factor 1, 35 kD subunit, NF cell stimulatory factor chain 1, NK cell stimulatory factor chain 1, NKSF1, p35

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.