product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Notum Protein, CF
catalog :
9118-NM-050
quantity :
50 ug
price :
618 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Guo F, Seldin M, Peterfy M, Charugundla S, Zhou Z, Lee S, et al. NOTUM promotes thermogenic capacity and protects against diet-induced obesity in male mice. Sci Rep. 2021;11:16409 pubmed publisher
product information
master code :
9118-NM
SKU :
9118-NM-050
product name :
Recombinant Human Notum Protein, CF
unit size :
50 ug
description :
The Recombinant Human Notum Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Notum Protein, CF has been validated for the following applications: Bioactivity.
target :
Notum
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
38-45 kDa, reducing conditions
theoretical molecular weight :
43 kDa
details of functionality :
Measured by its ability to inhibit Wnt induced TCF reporter activity in HEK293 human embryonic kidney cells. The ED50 for this effect is 0.1-0.6 ╡g/mL in the presence of 0.5 ╡g/mL of Recombinant Human Wnt-3a (Catalog # 5036-WN ).
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Human Notum Protein Bioactivity
accessionNumbers :
Q6P988
applications :
Bioactivity
source long :
Chinese Hamster Ovary cell line, CHO-derived human Notum protein Ser81-Thr451 (Cys330Ser) with a C-terminal 6-His tag
source short :
CHO
USD :
618 USD
alt names :
EC 3.-, notum pectinacetylesterase homolog (Drosophila), protein notum homolog
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.