This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human MMP-9 Protein, CF
catalog :
911-MP
quantity :
10 ug
price :
389 USD
citations: 23
Reference
NORWOOD TORO L, Wang Y, Condeelis J, Jones J, Backer J, Bresnick A. Myosin-IIA heavy chain phosphorylation on S1943 regulates tumor metastasis. Exp Cell Res. 2018;370:273-282 pubmed publisher
Hong M, Cheng H, Song L, Wang W, Wang Q, Xu D, et al. Wogonin Suppresses the Activity of Matrix Metalloproteinase-9 and Inhibits Migration and Invasion in Human Hepatocellular Carcinoma. Molecules. 2018;23: pubmed publisher
Kondo N, Temma T, Aita K, Shimochi S, Koshino K, Senda M, et al. Development of matrix metalloproteinase-targeted probes for lung inflammation detection with positron emission tomography. Sci Rep. 2018;8:1347 pubmed publisher
Dulyaninova N, Ruiz P, Gamble M, Backer J, Bresnick A. S100A4 regulates macrophage invasion by distinct myosin-dependent and myosin-independent mechanisms. Mol Biol Cell. 2018;29:632-642 pubmed publisher
Sasidhar M, Chevooru S, Eickelberg O, Hartung H, Neuhaus O. Downregulation of monocytic differentiation via modulation of CD147 by 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. PLoS ONE. 2017;12:e0189701 pubmed publisher
Gopcevic K, Rovcanin B, Kekic D, Milasinovic D, Kocic G, Stojanovic I. Gelatinases A and B and Antioxidant Enzyme Activity in the Early Phase of Acute Myocardial Infarction. Folia Biol (Praha). 2017;63:20-26 pubmed
Willumsen N, Bager C, Leeming D, Bay Jensen A, Karsdal M. Nidogen-1 Degraded by Cathepsin S can be Quantified in Serum and is Associated with Non-Small Cell Lung Cancer. Neoplasia. 2017;19:271-278 pubmed publisher
Svalina M, Kikuchi K, Abraham J, Lal S, Davare M, Settelmeyer T, et al. IGF1R as a Key Target in High Risk, Metastatic Medulloblastoma. Sci Rep. 2016;6:27012 pubmed publisher
Kim B, Jeong K, Kim J, Jin M, Kim J, Lee M, et al. Pathogenic Upregulation of Glial Lipocalin-2 in the Parkinsonian Dopaminergic System. J Neurosci. 2016;36:5608-22 pubmed publisher
Maetzler W, Deleersnijder W, Hanssens V, Bernard A, Brockmann K, Marquetand J, et al. GDF15/MIC1 and MMP9 Cerebrospinal Fluid Levels in Parkinson's Disease and Lewy Body Dementia. PLoS ONE. 2016;11:e0149349 pubmed publisher
Pei S, Yang X, Wang H, Zhang H, Zhou B, Zhang D, et al. Plantamajoside, a potential anti-tumor herbal medicine inhibits breast cancer growth and pulmonary metastasis by decreasing the activity of matrix metalloproteinase-9 and -2. BMC Cancer. 2015;15:965 pubmed publisher
Thorsen S, Christensen S, Würtz S, Lundberg M, Nielsen B, Vinther L, et al. Plasma levels of the MMP-9:TIMP-1 complex as prognostic biomarker in breast cancer: a retrospective study. BMC Cancer. 2013;13:598 pubmed publisher
Wang L, Cossette S, Rarick K, Gershan J, Dwinell M, Harder D, et al. Astrocytes directly influence tumor cell invasion and metastasis in vivo. PLoS ONE. 2013;8:e80933 pubmed publisher
Djokic J, Fagotto Kaufmann C, Bartels R, Nelea V, Reinhardt D. Fibulin-3, -4, and -5 are highly susceptible to proteolysis, interact with cells and heparin, and form multimers. J Biol Chem. 2013;288:22821-35 pubmed publisher
Hawkins K, Demars K, Yang C, Rosenberg G, Candelario Jalil E. Fluorometric immunocapture assay for the specific measurement of matrix metalloproteinase-9 activity in biological samples: application to brain and plasma from rats with ischemic stroke. Mol Brain. 2013;6:14 pubmed publisher
Devel L, Beau F, Amoura M, Vera L, Cassar Lajeunesse E, Garcia S, et al. Simple pseudo-dipeptides with a P2' glutamate: a novel inhibitor family of matrix metalloproteases and other metzincins. J Biol Chem. 2012;287:26647-56 pubmed publisher
Tsuchiya S, Simmer J, Hu J, Richardson A, Yamakoshi F, Yamakoshi Y. Astacin proteases cleave dentin sialophosphoprotein (Dspp) to generate dentin phosphoprotein (Dpp). J Bone Miner Res. 2011;26:220-8 pubmed publisher
Gonzalez R, Seurynck Servoss S, Crowley S, Brown M, Omenn G, Hayes D, et al. Development and validation of sandwich ELISA microarrays with minimal assay interference. J Proteome Res. 2008;7:2406-14 pubmed publisher
Zhao Z, McCloud B, Fleming R, Klempner M. Borrelia burgdorferi-induced monocyte chemoattractant protein-1 production in vivo and in vitro. Biochem Biophys Res Commun. 2007;358:528-33 pubmed
Gaggar A, Li Y, Weathington N, Winkler M, Kong M, Jackson P, et al. Matrix metalloprotease-9 dysregulation in lower airway secretions of cystic fibrosis patients. Am J Physiol Lung Cell Mol Physiol. 2007;293:L96-L104 pubmed
Borrelli V, di Marzo L, Sapienza P, Colasanti M, Moroni E, Cavallaro A. Role of platelet-derived growth factor and transforming growth factor beta1 the in the regulation of metalloproteinase expressions. Surgery. 2006;140:454-63 pubmed
Zhou B, Peyton M, He B, Liu C, Girard L, Caudler E, et al. Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer. Cancer Cell. 2006;10:39-50 pubmed
Levesque J, Hendy J, Winkler I, Takamatsu Y, Simmons P. Granulocyte colony-stimulating factor induces the release in the bone marrow of proteases that cleave c-KIT receptor (CD117) from the surface of hematopoietic progenitor cells. Exp Hematol. 2003;31:109-17 pubmed
product information
brand :
R&D Systems
master code :
911-MP
SKU :
911-MP-010
product name :
Recombinant Human MMP-9 Protein, CF
description :
The Recombinant Human MMP-9 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human MMP-9 Protein, CF has been validated for the following applications: Enzyme Activity.
target :
MMP-9
category :
Proteins and Enzymes
unit size :
10 ug
buffer :
Supplied as a 0.2 µm filtered solution in Tris, CaCl2, NaCl and Brij-35.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
observed molecular weight :
93 kDa, reducing conditions
theoretical molecular weight :
77 kDa
gene symbol :
MMP9
details of functionality :
Measured by its ability to cleave the fluorogenic peptide substrate, Mca-PLGL-Dpa-AR-NH2 (Catalog # ES001 ). The specific activity is 1,300 pmol/min/µg, as measured under the described conditions.
endotoxin note :
<1.1 EU per 1 µg of the protein by the LAL method.
catalog number base :
911-MP
accessionNumbers :
P14780
applications :
Enzyme Activity
source :
Chinese Hamster Ovary cell line, CHO-derived human MMP-9 protein Ala20-Asp707 (Gln279Arg)
2020 USD :
389
2021 USD :
389 USD
alt names :
92 kDa gelatinase, 92 kDa type IV collagenase, CLG4B, EC 3.4.24, EC 3.4.24.35, Gelatinase B, GELB, macrophage gelatinase, MANDP2, matrix metallopeptidase 9, matrix metalloproteinase 9, matrix metalloproteinase-9, MMP9, MMP-9, type V collagenase
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.