product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human MMP-9 Protein, CF
catalog :
911-MP-010
quantity :
10 ug
price :
491 USD
more info or order :
R&D Systems product webpage
citations: 31
Reference
Levengood M, Carosino C, Zhang X, Lucas S, Ortiz D, Westendorf L, et al. Preclinical development of SGN-CD47M: Protease-activated antibody technology enables selective tumor targeting of the innate immune checkpoint receptor CD47. Mol Cancer Ther. 2024;: pubmed publisher
Radosavljević T, Vukicevic D, Djureti x107 J, Gopcevic K, Labudović Borović M, Stankovic S, et al. The Role of Macrophage Inhibitory Factor in TAA-Induced Liver Fibrosis in Mice: Modulatory Effects of Betaine. Biomedicines. 2024;12: pubmed publisher
Huang J, Zhao C, Zhang S. Semaphorin 7A promotes endothelial permeability and inflammation via plexin C1 and integrin β1 in Kawasaki disease. BMC Pediatr. 2024;24:285 pubmed publisher
Chen X, Wang S, Xu W, Zhao M, Zhang Y, Xiao H. Metformin Directly Binds to MMP-9 to Improve Plaque Stability. J Cardiovasc Dev Dis. 2023;10: pubmed publisher
Giofr xe8 S, Renda A, Sesana S, Formicola B, Vergani B, Leone B, et al. Dual Functionalized Liposomes for Selective Delivery of Poorly Soluble Drugs to Inflamed Brain Regions. Pharmaceutics. 2022;14: pubmed publisher
Ju Y, Dai X, Tang Z, Ming Z, Ni N, Zhu D, et al. Verteporfin-mediated on/off photoswitching functions synergistically to treat choroidal vascular diseases. Bioact Mater. 2022;14:402-415 pubmed publisher
Larrouture Q, Cribbs A, Rao S, Philpott M, Snelling S, Knowles H. Loss of mutual protection between human osteoclasts and chondrocytes in damaged joints initiates osteoclast-mediated cartilage degradation by MMPs. Sci Rep. 2021;11:22708 pubmed publisher
Ozols M, Eckersley A, Platt C, Stewart McGuinness C, Hibbert S, Revote J, et al. Predicting Proteolysis in Complex Proteomes Using Deep Learning. Int J Mol Sci. 2021;22: pubmed publisher
Määttä M, Laurila H, Holopainen S, Aaltonen K, Lilja Maula L, Viitanen S, et al. Matrix metalloproteinase-2, -7, and -9 activities in dogs with idiopathic pulmonary fibrosis compared to healthy dogs and dogs with other respiratory diseases. J Vet Intern Med. 2021;35:462-471 pubmed publisher
Bluhmki T, Bitzer S, Gindele J, Schruf E, Kiechle T, Webster M, et al. Development of a miniaturized 96-Transwell air-liquid interface human small airway epithelial model. Sci Rep. 2020;10:13022 pubmed publisher
Mendes S, Amo Maestro L, Marino Puertas L, Diego I, Goulas T, Gomis Ruth F. Analysis of the inhibiting activity of reversion-inducing cysteine-rich protein with Kazal motifs (RECK) on matrix metalloproteinases. Sci Rep. 2020;10:6317 pubmed publisher
Hong M, Cheng H, Song L, Wang W, Wang Q, Xu D, et al. Wogonin Suppresses the Activity of Matrix Metalloproteinase-9 and Inhibits Migration and Invasion in Human Hepatocellular Carcinoma. Molecules. 2018;23: pubmed publisher
Kondo N, Temma T, Aita K, Shimochi S, Koshino K, Senda M, et al. Development of matrix metalloproteinase-targeted probes for lung inflammation detection with positron emission tomography. Sci Rep. 2018;8:1347 pubmed publisher
Sasidhar M, Chevooru S, Eickelberg O, Hartung H, Neuhaus O. Downregulation of monocytic differentiation via modulation of CD147 by 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. PLoS ONE. 2017;12:e0189701 pubmed publisher
Gopcevic K, Rovcanin B, Kekic D, Milasinovic D, Kocic G, Stojanovic I. Gelatinases A and B and Antioxidant Enzyme Activity in the Early Phase of Acute Myocardial Infarction. Folia Biol (Praha). 2017;63:20-26 pubmed
Willumsen N, Bager C, Leeming D, Bay Jensen A, Karsdal M. Nidogen-1 Degraded by Cathepsin S can be Quantified in Serum and is Associated with Non-Small Cell Lung Cancer. Neoplasia. 2017;19:271-278 pubmed publisher
Svalina M, Kikuchi K, Abraham J, Lal S, Davare M, Settelmeyer T, et al. IGF1R as a Key Target in High Risk, Metastatic Medulloblastoma. Sci Rep. 2016;6:27012 pubmed publisher
Kim B, Jeong K, Kim J, Jin M, Kim J, Lee M, et al. Pathogenic Upregulation of Glial Lipocalin-2 in the Parkinsonian Dopaminergic System. J Neurosci. 2016;36:5608-22 pubmed publisher
Maetzler W, Deleersnijder W, Hanssens V, Bernard A, Brockmann K, Marquetand J, et al. GDF15/MIC1 and MMP9 Cerebrospinal Fluid Levels in Parkinson's Disease and Lewy Body Dementia. PLoS ONE. 2016;11:e0149349 pubmed publisher
Pei S, Yang X, Wang H, Zhang H, Zhou B, Zhang D, et al. Plantamajoside, a potential anti-tumor herbal medicine inhibits breast cancer growth and pulmonary metastasis by decreasing the activity of matrix metalloproteinase-9 and -2. BMC Cancer. 2015;15:965 pubmed publisher
Thorsen S, Christensen S, Würtz S, Lundberg M, Nielsen B, Vinther L, et al. Plasma levels of the MMP-9:TIMP-1 complex as prognostic biomarker in breast cancer: a retrospective study. BMC Cancer. 2013;13:598 pubmed publisher
Wang L, Cossette S, Rarick K, Gershan J, Dwinell M, Harder D, et al. Astrocytes directly influence tumor cell invasion and metastasis in vivo. PLoS ONE. 2013;8:e80933 pubmed publisher
Djokic J, Fagotto Kaufmann C, Bartels R, Nelea V, Reinhardt D. Fibulin-3, -4, and -5 are highly susceptible to proteolysis, interact with cells and heparin, and form multimers. J Biol Chem. 2013;288:22821-35 pubmed publisher
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product information
master code :
911-MP
SKU :
911-MP-010
product name :
Recombinant Human MMP-9 Protein, CF
unit size :
10 ug
description :
The Recombinant Human MMP-9 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human MMP-9 Protein, CF has been validated for the following applications: Enzyme Activity.
target :
MMP-9
category :
Proteins and Enzymes
buffer :
Supplied as a 0.2 ╡m filtered solution in Tris, CaCl2, NaCl and Brij-35.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
observed molecular weight :
93 kDa, reducing conditions
theoretical molecular weight :
77 kDa
gene symbol :
MMP9
details of functionality :
Measured by its ability to cleave the fluorogenic peptide substrate, Mca-PLGL-Dpa-AR-NH2 (Catalog # ES001 ). The specific activity is 1,300 pmol/min/╡g, as measured under the described conditions.
endotoxin note :
<1.1 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Human MMP-9 Protein Enzyme Activity
accessionNumbers :
P14780
applications :
Enzyme Activity
source long :
Chinese Hamster Ovary cell line, CHO-derived human MMP-9 protein Ala20-Asp707 (Gln279Arg)
source short :
CHO
USD :
491 USD
alt names :
92 kDa gelatinase, 92 kDa type IV collagenase, CLG4B, EC 3.4.24, EC 3.4.24.35, Gelatinase B, GELB, macrophage gelatinase, MANDP2, matrix metallopeptidase 9, matrix metalloproteinase 9, matrix metalloproteinase-9, MMP9, MMP-9, type V collagenase
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.