Recombinant Mouse MMP-9 Protein, CF | R&D Systems 909-MM-010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse MMP-9 Protein, CF

catalog :

909-MM-010

quantity :

10 ug

price :

491 USD

citations: 20

Reference
Levengood M, Carosino C, Zhang X, Lucas S, Ortiz D, Westendorf L, et al. Preclinical development of SGN-CD47M: Protease-activated antibody technology enables selective tumor targeting of the innate immune checkpoint receptor CD47. Mol Cancer Ther. 2024;: pubmed publisher
Burmeister M, Frauenstein A, Kahms M, Arends L, Gerwien H, Deshpande T, et al. Secretomics reveals gelatinase substrates at the blood-brain barrier that are implicated in astroglial barrier function. Sci Adv. 2023;9:eadg0686 pubmed publisher
Kim E, Kim E, Shin D, Kim D, Choi S, Shin Y, et al. Carnosine Protects against Cerebral Ischemic Injury by Inhibiting Matrix-Metalloproteinases. Int J Mol Sci. 2021;22: pubmed publisher
Morichika D, Taniguchi A, Oda N, Fujii U, Senoo S, Itano J, et al. Loss of IL-33 enhances elastase-induced and cigarette smoke extract-induced emphysema in mice. Respir Res. 2021;22:150 pubmed publisher
Ren X, Hu H, Farooqi I, Simpkins J. Blood substitution therapy rescues the brain of mice from ischemic damage. Nat Commun. 2020;11:4078 pubmed publisher
Hui L, Nie Y, Li S, Guo M, Yang W, Huang R, et al. Matrix metalloproteinase 9 facilitates Zika virus invasion of the testis by modulating the integrity of the blood-testis barrier. PLoS Pathog. 2020;16:e1008509 pubmed publisher
Wang X, Rojas Quintero J, Wilder J, Tesfaigzi Y, Zhang D, Owen C. Tissue Inhibitor of Metalloproteinase-1 Promotes Polymorphonuclear Neutrophil (PMN) Pericellular Proteolysis by Anchoring Matrix Metalloproteinase-8 and -9 to PMN Surfaces. J Immunol. 2019;202:3267-3281 pubmed publisher
Jo Y, Kweon H, Kim D, Kim M, Kim S, Kim J, et al. Accelerated biodegradation of silk sutures through matrix metalloproteinase activation by incorporating 4-hexylresorcinol. Sci Rep. 2017;7:42441 pubmed publisher
Yuan G, Chen L, Feng J, Yang G, Ni Q, Xu X, et al. Dentin Sialoprotein is a Novel Substrate of Matrix Metalloproteinase 9 in vitro and in vivo. Sci Rep. 2017;7:42449 pubmed publisher
Weiss G, Lai C, Fife M, Grabiec A, Tildy B, Snelgrove R, et al. Reversal of TREM-1 ectodomain shedding and improved bacterial clearance by intranasal metalloproteinase inhibitors. Mucosal Immunol. 2017;10:1021-1030 pubmed publisher
Park M, Lee J, Kim N, Min W, Lee J, Kim K, et al. Neuropeptide Y Induces Hematopoietic Stem/Progenitor Cell Mobilization by Regulating Matrix Metalloproteinase-9 Activity Through Y1 Receptor in Osteoblasts. Stem Cells. 2016;34:2145-56 pubmed publisher
Raghuwanshi S, Smith N, Rivers E, Thomas A, Sutton N, Hu Y, et al. G protein-coupled receptor kinase 6 deficiency promotes angiogenesis, tumor progression, and metastasis. J Immunol. 2013;190:5329-36 pubmed publisher
Oh S, Jung S, Han J, Kim S, Kim J, Nam S, et al. Silibinin inhibits TPA-induced cell migration and MMP-9 expression in thyroid and breast cancer cells. Oncol Rep. 2013;29:1343-8 pubmed publisher
Song J, Wu C, Zhang X, Sorokin L. In vivo processing of CXCL5 (LIX) by matrix metalloproteinase (MMP)-2 and MMP-9 promotes early neutrophil recruitment in IL-1?-induced peritonitis. J Immunol. 2013;190:401-10 pubmed publisher
Suryawanshi A, Mulik S, Sharma S, Reddy P, Sehrawat S, Rouse B. Ocular neovascularization caused by herpes simplex virus type 1 infection results from breakdown of binding between vascular endothelial growth factor A and its soluble receptor. J Immunol. 2011;186:3653-65 pubmed publisher
Le Quement C, Guenon I, Gillon J, Valenca S, Cayron Elizondo V, Lagente V, et al. The selective MMP-12 inhibitor, AS111793 reduces airway inflammation in mice exposed to cigarette smoke. Br J Pharmacol. 2008;154:1206-15 pubmed publisher
Gaggar A, Jackson P, Noerager B, O Reilly P, McQuaid D, Rowe S, et al. A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation. J Immunol. 2008;180:5662-9 pubmed
Rafei M, Wu J, Annabi B, Lejeune L, Francois M, Galipeau J. A GMCSF and IL-15 fusokine leads to paradoxical immunosuppression in vivo via asymmetrical JAK/STAT signaling through the IL-15 receptor complex. Blood. 2007;109:2234-42 pubmed
Bruno M, Cuello A. Activity-dependent release of precursor nerve growth factor, conversion to mature nerve growth factor, and its degradation by a protease cascade. Proc Natl Acad Sci U S A. 2006;103:6735-40 pubmed
Bruemmer D, Collins A, Noh G, Wang W, Territo M, Arias Magallona S, et al. Angiotensin II-accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient mice. J Clin Invest. 2003;112:1318-31 pubmed

product information

master code :

909-MM

SKU :

909-MM-010

product name :

Recombinant Mouse MMP-9 Protein, CF

unit size :

10 ug

description :

The Recombinant Mouse MMP-9 Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse MMP-9 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

MMP-9

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Tris, CaCl2, NaCl and Brij-35.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Mouse

observed molecular weight :

80-105 kDa, reducing conditions

theoretical molecular weight :

78 kDa

gene symbol :

Mmp9

details of functionality :

Measured by its ability to cleave the fluorogenic peptide substrate, Mca-PLGL-Dpa-AR-NH2 (Catalog # ES001 ). The specific activity is 1,500 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Mouse MMP-9 Protein Enzyme Activity

accessionNumbers :

P41245

applications :

Enzyme Activity

source long :

Mouse myeloma cell line, NS0-derived mouse MMP-9 protein Ala20-Pro730

source short :

NS0

USD :

491 USD

alt names :

92 kDa gelatinase, 92 kDa type IV collagenase, CLG4B, EC 3.4.24, EC 3.4.24.35, Gelatinase B, GELB, macrophage gelatinase, MANDP2, matrix metallopeptidase 9, matrix metalloproteinase 9, matrix metalloproteinase-9, MMP9, MMP-9, type V collagenase

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.