Recombinant Human MBL Protein, CF | R&D Systems 9086-MB-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human MBL Protein, CF

catalog :

9086-MB-050

quantity :

50 ug

price :

423 USD

more info or order :

R&D Systems product webpage

citations: 7

Reference
De Marco Verissimo C, Jewhurst H, Dobó J, Gal P, Dalton J, Cwiklinski K. Fasciola hepatica is refractory to complement killing by preventing attachment of mannose binding lectin (MBL) and inhibiting MBL-associated serine proteases (MASPs) with serpins. PLoS Pathog. 2022;18:e1010226 pubmed publisher
Terävä J, Tiainen L, Lamminmaki U, Kellokumpu Lehtinen P, Pettersson K, Gidwani K. Lectin nanoparticle assays for detecting breast cancer-associated glycovariants of cancer antigen 15-3 (CA15-3) in human plasma. PLoS ONE. 2019;14:e0219480 pubmed publisher
Coumou J, Wagemakers A, Narasimhan S, Schuijt T, Ersoz J, Oei A, et al. The role of Mannose Binding Lectin in the immune response against Borrelia burgdorferi sensu lato. Sci Rep. 2019;9:1431 pubmed publisher
Martini F, Eckmair B, Stefanic S, Jin C, Garg M, Yan S, et al. Highly modified and immunoactive N-glycans of the canine heartworm. Nat Commun. 2019;10:75 pubmed publisher
Hammad N, El Badawy N, Ghramh H, Al Kady L. Mannose-Binding Lectin: A Potential Therapeutic Candidate against Candida Infection. Biomed Res Int. 2018;2018:2813737 pubmed publisher
Gunn B, Jones J, Shabman R, Whitmore A, Sarkar S, Blevins L, et al. Ross River virus envelope glycans contribute to disease through activation of the host complement system. Virology. 2018;515:250-260 pubmed publisher
Brazil J, Sumagin R, Stowell S, Lee G, Louis N, Cummings R, et al. Expression of Lewis-a glycans on polymorphonuclear leukocytes augments function by increasing transmigration. J Leukoc Biol. 2017;102:753-762 pubmed publisher

image

image 1 :

Recombinant Human MBL Protein Bioactivity

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

9086-MB

SKU :

9086-MB-050

product name :

Recombinant Human MBL Protein, CF

Description :

The Recombinant Human MBL Protein, CF from R&D Systems is derived from HEK293. The Recombinant Human MBL Protein, CF has been validated for the following applications: Bioactivity.

target :

MBL

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS and Trehalose.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

31-36 kDa, reducing conditions

theoretical molecular weight :

24 kDa

gene symbol :

MBL2

details of functionality :

Measured by its binding ability in a functional ELISA. When Mannan is immobilized at 0.1 µg/mL (100 µL/well), the concentration of Recombinant Human MBL that produces 50% of the optimal binding response is approximately 25-150 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

CAB56121

applications :

Bioactivity

source :

HEK293-derived Recombinant Human MBL Protein

USD :

423 USD

alt names :

COLEC1, COLEC1collectin-1, Collectin-1, HSMBPC, Mannan-binding protein, Mannose-binding lectin, mannose-binding lectin (protein C) 2, soluble, mannose-binding lectin (protein C) 2, soluble (opsonic defect), mannose-binding protein C, MBL2, MBL2D, MBLmannan-binding lectin, MBP, MBP1, MBP1mannose-binding lectin 2, soluble (opsonic defect), MBP-C, MGC116832, MGC116833

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage