Recombinant Human MMP-7 Protein, CF | R&D Systems 907-MP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human MMP-7 Protein, CF

catalog :

907-MP

quantity :

10 ug

price :

339 USD

citations: 8

Reference
Ye Y, Toczek J, Gona K, Kim H, Han J, Razavian M, et al. Novel Arginine-containing Macrocyclic MMP Inhibitors: Synthesis, 99mTc-labeling, and Evaluation. Sci Rep. 2018;8:11647 pubmed publisher
King S, Joshi H, Schjoldager K, Halim A, Madsen T, Dziegiel M, et al. Characterizing the O-glycosylation landscape of human plasma, platelets, and endothelial cells. Blood Adv. 2017;1:429-442 pubmed publisher
Willumsen N, Bager C, Leeming D, Bay Jensen A, Karsdal M. Nidogen-1 Degraded by Cathepsin S can be Quantified in Serum and is Associated with Non-Small Cell Lung Cancer. Neoplasia. 2017;19:271-278 pubmed publisher
Kristensen J, Karsdal M, Sand J, Willumsen N, Diefenbach C, Svensson B, et al. Serological assessment of neutrophil elastase activity on elastin during lung ECM remodeling. BMC Pulm Med. 2015;15:53 pubmed publisher
Djokic J, Fagotto Kaufmann C, Bartels R, Nelea V, Reinhardt D. Fibulin-3, -4, and -5 are highly susceptible to proteolysis, interact with cells and heparin, and form multimers. J Biol Chem. 2013;288:22821-35 pubmed publisher
Szarvas T, Singer B, Becker M, vom Dorp F, Jager T, Szendroi A, et al. Urinary matrix metalloproteinase-7 level is associated with the presence of metastasis in bladder cancer. BJU Int. 2011;107:1069-73 pubmed publisher
Hawinkels L, Verspaget H, Van den Berg M, Hanemaaijer R, Sier C. Determination of matrilysin activity in gastrointestinal neoplasia. Eur J Clin Invest. 2007;37:598-9 pubmed
Zhou B, Peyton M, He B, Liu C, Girard L, Caudler E, et al. Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer. Cancer Cell. 2006;10:39-50 pubmed

product information

brand :

R&D Systems

master code :

907-MP

SKU :

907-MP-010

product name :

Recombinant Human MMP-7 Protein, CF

description :

The Recombinant Human MMP-7 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human MMP-7 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

MMP-7

category :

Proteins and Enzymes

unit size :

10 ug

buffer :

Supplied as a 0.2 µm filtered solution in MES, NaCl and CaCl2.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

28 kDa (major) 20 kDa (minor), reducing conditions

theoretical molecular weight :

28 kDa 20 kDa (Leu18-T198)

gene symbol :

MMP7

details of functionality :

Measured by its ability to cleave the fluorogenic peptide substrate, Mca-PLGL-Dpa-AR-NH2 (Catalog # ES001 ). The specific activity is 600 pmol/min/µg, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

catalog number base :

907-MP

accessionNumbers :

P09237

applications :

Enzyme Activity

source :

Mouse myeloma cell line, NS0-derived human MMP-7 protein Leu18-Lys267

2020 USD :

339

2021 USD :

339 USD

alt names :

EC 3.4.24, EC 3.4.24.23, matrilysin, Matrin, matrix metallopeptidase 7 (matrilysin, uterine), matrix metalloproteinase 7 (matrilysin, uterine), Matrix metalloproteinase-7, MMP7, MMP-7, MPSL1, PUMP1, PUMP-1, Pump-1 protease, uterine matrilysin, Uterine metalloproteinase

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 °C as supplied. 3 months, -70 °C under sterile conditions after opening.