product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Neuroligin 3/NLGN3 Protein, CF
catalog :
9069-NL-050
quantity :
50 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Camporesi E, Lashley T, Gobom J, Lantero Rodriguez J, Hansson O, Zetterberg H, et al. Neuroligin-1 in brain and CSF of neurodegenerative disorders: investigation for synaptic biomarkers. Acta Neuropathol Commun. 2021;9:19 pubmed publisher
Goranci Buzhala G, Mariappan A, Gabriel E, Ramani A, Ricci Vitiani L, Buccarelli M, et al. Rapid and Efficient Invasion Assay of Glioblastoma in Human Brain Organoids. Cell Rep. 2020;31:107738 pubmed publisher
Brito Moreira J, Lourenco M, Oliveira M, Ribeiro F, Ledo J, Diniz L, et al. Interaction of amyloid-β (Aβ) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice. J Biol Chem. 2017;292:7327-7337 pubmed publisher
product information
master code :
9069-NL
SKU :
9069-NL-050
product name :
Recombinant Human Neuroligin 3/NLGN3 Protein, CF
unit size :
50 ug
description :
The Recombinant Human Neuroligin 3/NLGN3 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Neuroligin 3/NLGN3 Protein, CF has been validated for the following applications: Bioactivity.
target :
Neuroligin 3/NLGN3
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
87-101 kDa, reducing conditions
theoretical molecular weight :
76 kDa
gene symbol :
NLGN3
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Human Neuroligin 3/NLGN3 is immobilized at 2 ╡g/mL, Biotinylated Recombinant Human Neurexin 1 beta Fc Chimera binds with a typical ED50 = 150-900 ng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Human Neuroligin 3/NLGN3 Protein Bioactivity
accessionNumbers :
Q9NZ94
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived human Neuroligin 3/NLGN3 protein Ala39-Ser709 (Ser92Tyr), with a C-terminal 6-His tag
source short :
NS0
USD :
432 USD
alt names :
ASPGX1, AUTSX1, Gliotactin homolog, HNL3, KIAA1480HNL3, neuroligin 3, neuroligin-3, NL3, NLGN3
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.