Recombinant Mouse PD-L1/B7-H1 His-tag Protein, CF | R&D Systems 9048-B7-100 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse PD-L1/B7-H1 His-tag Protein, CF

catalog :

9048-B7-100

quantity :

100 ug

price :

434 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Cai E, Beppler C, Eichorst J, Marchuk K, Eastman S, Krummel M. T cells use distinct topographical and membrane receptor scanning strategies that individually coalesce during receptor recognition. Proc Natl Acad Sci U S A. 2022;119:e2203247119 pubmed publisher
Du S, McCall N, Park K, Guan Q, Fontina P, Ertel A, et al. Blockade of Tumor-Expressed PD-1 promotes lung cancer growth. Oncoimmunology. 2018;7:e1408747 pubmed publisher

image

image 1 :

Recombinant Mouse PD-L1/B7-H1 His-tag Protein Binding Activity

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

9048-B7

SKU :

9048-B7-100

product name :

Recombinant Mouse PD-L1/B7-H1 His-tag Protein, CF

Description :

The Recombinant Mouse PD-L1/B7-H1 His-tag Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse PD-L1/B7-H1 His-tag Protein, CF has been validated for the following applications: Bioactivity.

target :

PD-L1/B7-H1

category :

Proteins and Enzymes

unit size :

100 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Mouse

observed molecular weight :

49-62 kDa, reducing conditions

theoretical molecular weight :

26 kDa

gene symbol :

Cd274

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Mouse PD-L1/B7-H1 is immobilized at 25 ng/mL (100 µL/well), the concentration of Recombinant Mouse PD-1 Fc Chimera (Catalog # 1021-PD ) that produces 50% of the optimal binding response is approximately 8-40 ng/mL

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q9EP73

applications :

Bioactivity

source :

NS0-derived Recombinant Mouse PD-L1/B7-H1 His-tag Protein

USD :

434 USD

alt names :

Avelumab, B7-H, B7H1, B7-H1, B7H1PDCD1L1, CD274, CD274 antigenMGC142294, CD274 molecule, PDCD1L1, PDCD1LG1, PDCD1LG1MGC142296, PDL1, PD-L1, PD-L1B7 homolog 1, PDL1PDCD1 ligand 1, programmed cell death 1 ligand 1, Programmed death ligand 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage