product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Viral 136R/Y136 Protein, CF
catalog :
8976-BR-025/CF
quantity :
25 ug
price :
443 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Ardanuy J, Scanlon K, Skerry C, Fuchs S, Carbonetti N. Age-Dependent Effects of Type I and Type III IFNs in the Pathogenesis of Bordetella pertussis Infection and Disease. J Immunol. 2020;204:2192-2202 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne brand
catalog number base :
8976-BR/CF
SKU :
8976-BR-025/CF
product name :
Recombinant Viral 136R/Y136 Protein, CF
description :
The Recombinant Viral 136R/Y136 Protein, CF from R&D Systems is derived from CHO. The Recombinant Viral 136R/Y136 Protein, CF has been validated for the following applications: Bioactivity.
target :
136R
unit size :
25 ug
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Viral
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
observed molecular weight :
88-120 kDa, reducing conditions
theoretical molecular weight :
41 kDa
details of functionality :
Measured by its ability to inhibit Type-I and Type-III IFN-mediated anti-viral activity. Huang, J. et al . (2007) PANS 104 :9822. The ED50 for this effect is 2-12 ng/mL in the presence of 20 pg/mL Recombinant Human IFN¿ß (Catalog # 8499-IF ).
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
applications :
Bioactivity
product keywords :
8976-BR, rv136R, v136R, carrier-free, carrier free, 8976BR/CF, IFN-alpha/beta R, IFN-alpha/beta-receptor-like secreted glycoprotein, IFN-alpha/beta receptor-like secreted glycoprotein
source :
CHO-derived Recombinant Viral 136R/Y136 Protein, CF
extended description :
Type I and III Interferon Inhibitor
USD :
434
USD 2025 :
443 USD
product details :
Type I and III Interferon Inhibitor
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.