Recombinant Human Active p70 S6 Kinase Protein, CF | R&D Systems 896-KS-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Active p70 S6 Kinase Protein, CF

catalog :

896-KS-010

quantity :

10 ug

price :

453 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Chen M, Wan L, Zhang J, Zhang J, Méndez L, Clohessy J, et al. Deregulated PP1α phosphatase activity towards MAPK activation is antagonized by a tumor suppressive failsafe mechanism. Nat Commun. 2018;9:159 pubmed publisher
Lu X, Horner J, Paul E, Shang X, Troncoso P, Deng P, et al. Effective combinatorial immunotherapy for castration-resistant prostate cancer. Nature. 2017;543:728-732 pubmed publisher
Lee H, Mustafa A, Hudes G, Kruger W. Hydroxychloroquine Destabilizes Phospho-S6 in Human Renal Carcinoma Cells. PLoS ONE. 2015;10:e0131464 pubmed publisher
Ip C, Cheung A, Ngan H, Wong A. p70 S6 kinase in the control of actin cytoskeleton dynamics and directed migration of ovarian cancer cells. Oncogene. 2011;30:2420-32 pubmed publisher

image

image 1 :

Recombinant Human Active p70 S6 Kinase Protein SDS-PAGE

product information

brand :

R&D Systems

master code :

896-KS

SKU :

896-KS-010

product name :

Recombinant Human Active p70 S6 Kinase Protein, CF

description :

The Recombinant Human Active p70 S6 Kinase Protein, CF from R&D Systems is derived from Sf 9 (baculovirus). The Recombinant Human Active p70 S6 Kinase Protein, CF has been validated for the following applications: Bioactivity.

target :

p70 S6 Kinase

category :

Proteins and Enzymes

sizes available :

10 ug

buffer :

Supplied in 50 mM sodium phosphate (pH 7.0), 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, and 25% glycerol.

conjugate :

Unconjugated

purity :

>85%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain at 5 µg per lane.

species :

Human

observed molecular weight :

76 kDa

gene symbol :

RPS6KB1

details of functionality :

The activity of p70S6K was determined to be 73 nmol/min/mg using a synthetic peptide substrate.

accessionNumbers :

NM_003161

applications :

Bioactivity

source :

Sf 9 (baculovirus)-derived Recombinant Human Active p70 S6 Kinase Protein, CF

USD :

453 USD

alt names :

EC 2.7.11, EC 2.7.11.1, p70 ribosomal S6 kinase alpha, p70 S6 kinase alpha, p70 S6 kinase, alpha 1,70 kDa ribosomal protein S6 kinase 1, p70 S6 kinase, alpha 2, p70 S6KA, p70 S6K-alpha, p70(S6K)-alpha, p70-alpha, p70-S6K, P70S6K1, PS6K, ribosomal protein S6 kinase beta-1, Ribosomal protein S6 kinase I, ribosomal protein S6 kinase, 70kD, polypeptide 1, ribosomal protein S6 kinase, 70kDa, polypeptide 1, RPS6KB1, S6K, S6K1, S6K1p70-S6K 1, S6K-beta-1, serine/threonine kinase 14 alpha, Serine/threonine-protein kinase 14A, STK14A

storage :

This product is stable at Avoid repeated freeze-thaw cycles.

more info or order :

R&D Systems product webpage