Recombinant Human IL-6/IL-6R alpha Protein Chimera | R&D Systems 8954-SR product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IL-6/IL-6R alpha Protein Chimera

catalog :

8954-SR

quantity :

25 ug

price :

349 USD

citations: 1

Reference
Kretschmer T, Schulze Edinghausen M, Turnwald E, Janoschek R, Bae Gartz I, Zentis P, et al. Effect of Maternal Obesity in Mice on IL-6 Levels and Placental Endothelial Cell Homeostasis. Nutrients. 2020;12: pubmed publisher

product information

brand :

R&D Systems

master code :

8954-SR

SKU :

8954-SR-025

product name :

Recombinant Human IL-6/IL-6R alpha Protein Chimera

description :

The Recombinant Human IL-6/IL-6R alpha Protein Chimera from R&D Systems is derived from HEK293. The Recombinant Human IL-6/IL-6R alpha Protein Chimera has been validated for the following applications: Bioactivity.

target :

IL-6R alpha

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

78-93 kDa, reducing conditions

theoretical molecular weight :

59 kDa

gene symbol :

IL6

details of functionality :

Measured by its ability to inhibit M1 mouse myeloid leukemia cell proliferation. The ED50 for this effect is 2.5-12.5 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

8954-SR

accessionNumbers :

P08887 (IL-6 R alpha) P05231 (IL-6)

applications :

Bioactivity

source :

Human embryonic kidney cell, HEK293-derived human IL-6/IL-6R alpha Complex protein Human IL-6R alpha (Leu20-Asp358) Accession # P08887 GGGSGGGSGGGS Human IL-6 Val30-Met212 Accession # P05231 N-terminus C-terminus

2020 USD :

349

2021 USD :

349 USD

alt names :

BSF2, BSF-2, CD126, gp80, IFNB2, IL6, IL-6 R alpha, IL6Q, IL6R, IL6R alpha, IL-6R-1, IL6RA, IL-6RA, IL6RQ, interleukin 6 receptor, MGI-2A

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.