Recombinant Human NELL2 Protein, CF | R&D Systems 8946-NL-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human NELL2 Protein, CF

catalog :

8946-NL-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Jones K, Keddy C, Jenkins C, Nicholson K, Shinde U, Davare M. Novel insight into mechanisms of ROS1 catalytic activation via loss of the extracellular domain. Sci Rep. 2024;14:22191 pubmed publisher
Jayabal P, Zhou F, Lei X, Ma X, Blackman B, Weintraub S, et al. NELL2-cdc42 signaling regulates BAF complexes and Ewing sarcoma cell growth. Cell Rep. 2021;36:109254 pubmed publisher

product information

master code :

8946-NL

SKU :

8946-NL-050

product name :

Recombinant Human NELL2 Protein, CF

unit size :

50 ug

description :

The Recombinant Human NELL2 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human NELL2 Protein, CF has been validated for the following applications: Bioactivity.

target :

NELL2

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Sodium Citrate, NaCl and EDTA.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

100-125 kDa, reducing conditions

theoretical molecular weight :

90 kDa

gene symbol :

NELL2

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is 0.3-1.8 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q99435

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human NELL2 protein Leu22-Leu816, with a C-terminal 6-His tag

source short :

NS0

USD :

432 USD

alt names :

Mel91, nel (chicken)-like 2, NEL-like 2 (chicken), NEL-like protein 2, Nel-related protein 2, NRP2, NRP2neural epidermal growth factor-like 2, protein kinase C-binding protein NELL2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage