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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human IL-11 R alpha Protein, CF
catalog :
8895-MR-050
quantity :
50 ug
price :
410 USD
more info or order :
citations: 3
Reference
Lindkvist M, Zegeye M, Greneg xe5 rd M, Ljungberg L. Pleiotropic, Unique and Shared Responses Elicited by IL-6 Family Cytokines in Human Vascular Endothelial Cells. Int J Mol Sci. 2022;23: pubmed publisher
Dong J, Viswanathan S, Adami E, Singh B, Chothani S, Ng B, et al. Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH. Nat Commun. 2021;12:66 pubmed publisher
Aryappalli P, Shabbiri K, Masad R, Al Marri R, Haneefa S, Mohamed Y, et al. Inhibition of Tyrosine-Phosphorylated STAT3 in Human Breast and Lung Cancer Cells by Manuka Honey is Mediated by Selective Antagonism of the IL-6 Receptor. Int J Mol Sci. 2019;20: pubmed publisher
product information
brand :
R&D Systems
master code :
8895-MR
SKU :
8895-MR-050
product name :
Recombinant Human IL-11 R alpha Protein, CF
description :
The Recombinant Human IL-11 R alpha Protein, CF from R&D Systems is derived from CHO. The Recombinant Human IL-11 R alpha Protein, CF has been validated for the following applications: Bioactivity.
target :
IL-11 R alpha
category :
Proteins and Enzymes
sizes available :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
40-55 kDa, reducing conditions
theoretical molecular weight :
38 kDa
gene symbol :
IL11RA
details of functionality :
Measured by its ability to bind recombinant human IL-11 in a functional ELISA with an estimated Kd 1 nM.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q14626
applications :
Bioactivity
source :
CHO-derived Recombinant Human IL-11 R alpha Protein, CF
USD :
410
USD 2023 :
410 USD
alt names :
AI314697, GP130, IL11R alpha, IL11RA, IL-11RA, Il11ra2, NR1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.