Recombinant Human UNC5B Protein Fc Chimera, CF | R&D Systems 8869-UN product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human UNC5B Protein Fc Chimera, CF

catalog :

8869-UN

quantity :

50 ug

price :

359 USD

citations: 2

Reference
Yamada M, Fujita Y, Hayano Y, Hayakawa H, Baba K, Mochizuki H, et al. Increased Expression of Fibronectin Leucine-Rich Transmembrane Protein 3 in the Dorsal Root Ganglion Induces Neuropathic Pain in Rats. J Neurosci. 2019;39:7615-7627 pubmed publisher
Tai Nagara I, Yoshikawa Y, Numata N, Ando T, Okabe K, Sugiura Y, et al. Placental labyrinth formation in mice requires endothelial FLRT2/UNC5B signaling. Development. 2017;144:2392-2401 pubmed publisher

product information

brand :

R&D Systems

master code :

8869-UN

SKU :

8869-UN-050

product name :

Recombinant Human UNC5B Protein Fc Chimera, CF

description :

The Recombinant Human UNC5B Protein Fc Chimera, CF from R&D Systems is derived from CHO. The Recombinant Human UNC5B Protein Fc Chimera, CF has been validated for the following applications: Bioactivity.

target :

UNC5H2/UNC5B

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE with silver staining.

species :

Human

theoretical molecular weight :

66 kDa (monomer)

gene symbol :

UNC5B

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human UNC5H2/UNC5B Fc Chimera is immobilized at 2 µg/mL (100 µL/well), the concentration of Recombinant Mouse Netrin-1 (Catalog # 1109-N1 ) that produces 50% optimal binding response is approximately 7-42 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

8869-UN

accessionNumbers :

Q8IZJ1

applications :

Bioactivity

source :

Chinese Hamster Ovary cell line, CHO-derived human UNC5H2/UNC5B protein Human UNC5H2/UNC5B (Gly27-Tyr377) Accession # Q8IZJ1 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

2020 USD :

359

2021 USD :

359 USD

alt names :

p53RDL1, p53-regulated receptor for death and life protein 1, Protein unc-5 homolog 2, Protein unc-5 homolog B, transmembrane receptor Unc5H2, unc5 (C.elegans homolog) b, unc-5 homolog 2, unc-5 homolog B (C. elegans), UNC5B, UNC5H2netrin receptor UNC5B

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.