Recombinant Human UNC5B Protein Fc Chimera, CF | R&D Systems 8869-UN-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human UNC5B Protein Fc Chimera, CF

catalog :

8869-UN-050

quantity :

50 ug

price :

456 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Boyé K, Geraldo L, Furtado J, Pibouin Fragner L, Poulet M, Kim D, et al. Endothelial Unc5B controls blood-brain barrier integrity. Nat Commun. 2022;13:1169 pubmed publisher
Yamada M, Fujita Y, Hayano Y, Hayakawa H, Baba K, Mochizuki H, et al. Increased Expression of Fibronectin Leucine-Rich Transmembrane Protein 3 in the Dorsal Root Ganglion Induces Neuropathic Pain in Rats. J Neurosci. 2019;39:7615-7627 pubmed publisher
Tai Nagara I, Yoshikawa Y, Numata N, Ando T, Okabe K, Sugiura Y, et al. Placental labyrinth formation in mice requires endothelial FLRT2/UNC5B signaling. Development. 2017;144:2392-2401 pubmed publisher

product information

brand :

R&D Systems

master code :

8869-UN

SKU :

8869-UN-050

product name :

Recombinant Human UNC5B Protein Fc Chimera, CF

unit size :

50 ug

seo description :

The Recombinant Human UNC5B Protein Fc Chimera, CF from R&D Systems is derived from CHO. The Recombinant Human UNC5B Protein Fc Chimera, CF has been validated for the following applications: Bioactivity.

target :

UNC5H2/UNC5B

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE with silver staining.

species :

Human

theoretical molecular weight :

66 kDa (monomer)

gene symbol :

UNC5B

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human UNC5H2/UNC5B Fc Chimera is immobilized at 2 ╡g/mL (100 ╡L/well), the concentration of Recombinant Mouse Netrin-1 (Catalog # 1109-N1 ) that produces 50% optimal binding response is approximately 7-42 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q8IZJ1

applications :

Bioactivity

source :

CHO-derived Recombinant Human UNC5B Protein Fc Chimera, CF

USD :

456 USD

alt names :

p53RDL1, p53-regulated receptor for death and life protein 1, Protein unc-5 homolog 2, Protein unc-5 homolog B, transmembrane receptor Unc5H2, unc5 (C.elegans homolog) b, unc-5 homolog 2, unc-5 homolog B (C. elegans), UNC5B, UNC5H2netrin receptor UNC5B

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage