Recombinant Mouse BID (Caspase-8-cleaved) Protein, CF | R&D Systems 883-M8-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse BID (Caspase-8-cleaved) Protein, CF

catalog :

883-M8-050

quantity :

50 ug

price :

468 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Serasinghe M, Missert D, Asciolla J, Podgrabinska S, Wieder S, Izadmehr S, et al. Anti-apoptotic BCL-2 proteins govern cellular outcome following B-RAF(V600E) inhibition and can be targeted to reduce resistance. Oncogene. 2015;34:857-67 pubmed publisher
Alymova I, Samarasinghe A, Vogel P, Green A, Weinlich R, McCullers J. A novel cytotoxic sequence contributes to influenza A viral protein PB1-F2 pathogenicity and predisposition to secondary bacterial infection. J Virol. 2014;88:503-15 pubmed publisher
Kook S, Zhan X, Cleghorn W, Benovic J, Gurevich V, Gurevich E. Caspase-cleaved arrestin-2 and BID cooperatively facilitate cytochrome C release and cell death. Cell Death Differ. 2014;21:172-84 pubmed publisher
Valentijn A, Gilmore A. Translocation of full-length Bid to mitochondria during anoikis. J Biol Chem. 2004;279:32848-57 pubmed

product information

brand :

R&D Systems

master code :

883-M8

SKU :

883-M8-050

product name :

Recombinant Mouse BID (Caspase-8-cleaved) Protein, CF

unit size :

50 ug

seo description :

The Recombinant Mouse BID (Caspase-8-cleaved) Protein, CF from R&D Systems is derived from E. coli. The Recombinant Mouse BID (Caspase-8-cleaved) Protein, CF has been validated for the following applications: Bioactivity.

target :

BID

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in HEPES-KOH and KCl.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

7 kDa and 15 kDa, under reducing and non-reducing conditions

theoretical molecular weight :

7 kDa (N-terminal fragment) 15 kDa (C-terminal fragment)

gene symbol :

Bid

details of functionality :

Measured by its ability to induce cytochromeác release from isolated mouse liver mitochondria. The typical EC50 for cytochrome c releasing activity is 100 nM. Cytochrome c is quantified using the Rat/Mouse Cytochrome c Quantikine« ELISA Kit (Catalog # MCTC0 ). The EC50 for the desired application should be determined. Uncleaved Recombinant Mouse BID is available (Catalog # 860-MB ).

accessionNumbers :

P70444

applications :

Bioactivity

source :

E. coli-derived Recombinant Mouse BID (Caspase-8-cleaved) Protein, CF

USD :

468 USD

alt names :

apoptic death agonist, BH3 interacting domain death agonist, BH3-interacting domain death agonist, BID isoform ES(1b), BID isoform L(2), BID isoform Si6, desmocollin type 4, FP497, Human BID coding sequence, MGC15319, MGC42355, p22 BID, tbid

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage