product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human IGFBP-5 Protein, CF
catalog :
875-B5-025
quantity :
25 ug
price :
407 USD
more info or order :
citations: 11
Reference |
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Wirthgen E, Goumon S, Kunze M, Walz C, Spitschak M, Tuchscherer A, et al. Effects of Transport Duration and Environmental Conditions in Winter or Summer on the Concentrations of Insulin-Like Growth Factors and Insulin-Like Growth Factor-Binding Proteins in the Plasma of Market-Weight Pigs. Front Endocrinol (Lausanne). 2018;9:36 pubmed publisher
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Han N, Zhang F, Li G, Zhang X, Lin X, Yang H, et al. Local application of IGFBP5 protein enhanced periodontal tissue regeneration via increasing the migration, cell proliferation and osteo/dentinogenic differentiation of mesenchymal stem cells in an inflammatory niche. Stem Cell Res Ther. 2017;8:210 pubmed publisher
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McCaig C, Duval C, Hemers E, Steele I, Pritchard D, Przemeck S, et al. The role of matrix metalloproteinase-7 in redefining the gastric microenvironment in response to Helicobacter pylori. Gastroenterology. 2006;130:1754-63 pubmed
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Cortesio C, Jiang W. Mannan-binding lectin-associated serine protease 3 cleaves synthetic peptides and insulin-like growth factor-binding protein 5. Arch Biochem Biophys. 2006;449:164-70 pubmed
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Nakamura M, Miyamoto S, Maeda H, Ishii G, Hasebe T, Chiba T, et al. Matrix metalloproteinase-7 degrades all insulin-like growth factor binding proteins and facilitates insulin-like growth factor bioavailability. Biochem Biophys Res Commun. 2005;333:1011-6 pubmed
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product information
master code :
875-B5
SKU :
875-B5-025
product name :
Recombinant Human IGFBP-5 Protein, CF
unit size :
25 ug
description :
The Recombinant Human IGFBP-5 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human IGFBP-5 Protein, CF has been validated for the following applications: Bioactivity.
target :
IGFBP-5
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in Acetonitrile and TFA.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
observed molecular weight :
35-37 kDa, reducing conditions
theoretical molecular weight :
28-29 kDa
gene symbol :
IGFBP5
details of functionality :
Measured by its ability to inhibit the biological activity of IGF-I or IGF-II on MCF-7 human breast cancer cells. Karey, K.P. et al . (1988) Cancer Research 48 :4083. The ED50 for this effect is 0.5-1.5á╡g/mL in the presence of 14áng/mL rhIGF-II.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P24593
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived human IGFBP-5 protein Leu21-Glu272, with an N-terminal Met
source short :
NS0
USD :
407 USD
alt names :
IBP5IBP-5, IGF-binding protein 5, IGFBP5, IGFBP-5, insulin-like growth factor binding protein 5, insulin-like growth factor-binding protein 5
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information

R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.
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