product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human IL-10 R beta Fc Chimera Protein, CF
catalog :
874-RB-100
quantity :
100 ug
price :
564 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Santer D, Minty G, Golec D, Lu J, May J, Namdar A, et al. Differential expression of interferon-lambda receptor 1 splice variants determines the magnitude of the antiviral response induced by interferon-lambda 3 in human immune cells. PLoS Pathog. 2020;16:e1008515 pubmed publisher
Donnelly R, Sheikh F, Kotenko S, Dickensheets H. The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain. J Leukoc Biol. 2004;76:314-21 pubmed
product information
master code :
874-RB
SKU :
874-RB-100
product name :
Recombinant Human IL-10 R beta Fc Chimera Protein, CF
unit size :
100 ug
description :
The Recombinant Human IL-10 R beta Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human IL-10 R beta Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
IL-10 R beta
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
observed molecular weight :
75-85 kDa, reducing conditions
theoretical molecular weight :
51 kDa (monomer)
gene symbol :
IL10RB
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Human IL 28 R alpha/IFN lambda R1 Fc Chimera (Catalog # 5260-MR ) is immobilized at 5.00 ╡g/mL (100 ╡L/well), the concentration of Recombinant Human IL-10 R beta Fc Chimera that produces 50% of the optimal binding response is found to be approximately 0.300-3.00 ╡g/mL.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q08334
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived human IL-10 R beta protein Human IL-10 R▀ (Met20-Ser220) Accession # Q08334 DIEGRMD Human IgG1 (Pro100-Lys330) 6-His tag N-terminus C-terminus
source short :
NS0
USD :
564 USD
alt names :
CDw210b, CDw210b antigen, CRF2-4IL-10R subunit 2, CRFB4, CRFB4human transmembrane receptor protein; cytokine receptor10CDW210B, D21S58, D21S66, IBD25, IL-10 receptor subunit beta, IL10R beta, IL-10R2, IL-10R2IL-10R subunit beta, IL10RB, IL-10RB, interleukin 10 receptor, beta, Interleukin-10 receptor subunit 2, interleukin-10 receptor subunit beta, member 4
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.