Recombinant Human IGFBP-1 Protein, CF | R&D Systems 871-B1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IGFBP-1 Protein, CF

catalog :

871-B1

quantity :

25 ug

price :

329 USD

citations: 5

Reference
Bak D, Choi M, Kim S, Lee B, Kim J, Jeon E, et al. Human umbilical cord blood mesenchymal stem cells engineered to overexpress growth factors accelerate outcomes in hair growth. Korean J Physiol Pharmacol. 2018;22:555-566 pubmed publisher
Lu J, Liu K, Schulz N, Karampelias C, Charbord J, Hilding A, et al. IGFBP1 increases ?-cell regeneration by promoting ?- to ?-cell transdifferentiation. EMBO J. 2016;35:2026-44 pubmed publisher
Borai A, Livingstone C, Mehta S, Zarif H, Abdelaal F, Ferns G. Biological variation in fasting serum insulin-like growth factor binding protein-1 (IGFBP-1) among individuals with a varying glucose tolerance. Clin Biochem. 2009;42:1270-4 pubmed publisher
Cortesio C, Jiang W. Mannan-binding lectin-associated serine protease 3 cleaves synthetic peptides and insulin-like growth factor-binding protein 5. Arch Biochem Biophys. 2006;449:164-70 pubmed
Nakamura M, Miyamoto S, Maeda H, Ishii G, Hasebe T, Chiba T, et al. Matrix metalloproteinase-7 degrades all insulin-like growth factor binding proteins and facilitates insulin-like growth factor bioavailability. Biochem Biophys Res Commun. 2005;333:1011-6 pubmed

product information

brand :

R&D Systems

master code :

871-B1

SKU :

871-B1-025

product name :

Recombinant Human IGFBP-1 Protein, CF

description :

The Recombinant Human IGFBP-1 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human IGFBP-1 Protein, CF has been validated for the following applications: Bioactivity.

target :

IGFBP-1

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

32 kDa, reducing conditions

theoretical molecular weight :

25 kDa

gene symbol :

IGFBP1

details of functionality :

Measured by its ability to inhibit the biological activity of IGF-I or IGF-II on MCF-7 human breast cancer cells. Karey, K.P. et al . (1988) Cancer Research 48 :4083. The ED50 for this effect is typically 0.1-0.6 µg/mL in the presence of 6 ng/mL recombinant human IGF-I.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

871-B1

accessionNumbers :

P08833

applications :

Bioactivity

source :

Mouse myeloma cell line, NS0-derived human IGFBP-1 protein Ala26-Asn259

2020 USD :

329

2021 USD :

329 USD

alt names :

alpha-pregnancy-associated endometrial globulin, amniotic fluid binding protein, binding protein-25, binding protein-26, binding protein-28, growth hormone independent-binding protein, hIGFBP-1, IBP1, IBP-1, IGF-binding protein 1, IGFBP1, IGFBP-1, IGF-BP25, insulin-like growth factor binding protein 1, insulin-like growth factor-binding protein 1, Placental protein 12, PP12AFBP

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.