Recombinant Human VCAM-1/CD106 Fc Chimera Protein, CF | R&D Systems 862-VC-100 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human VCAM-1/CD106 Fc Chimera Protein, CF

catalog :

862-VC-100

quantity :

100 ug

price :

425 USD

more info or order :

R&D Systems product webpage

citations: 25

Reference
Ullo M, D Amico A, Lavenus S, Logue J. The amoeboid migration of monocytes in confining channels requires the local remodeling of the cortical actin cytoskeleton by cofilin-1. Res Sq. 2023;: pubmed publisher
Ullo M, D Amico A, Lavenus S, Logue J. The amoeboid migration of monocytes in confining channels requires the local remodeling of the cortical actin cytoskeleton by cofilin-1. bioRxiv. 2023;: pubmed publisher
Wilkins G, Gilmour J, Giannoudaki E, Kirby J, Sheerin N, Ali S. Dissecting the Therapeutic Mechanisms of Sphingosine-1-Phosphate Receptor Agonism during Ischaemia and Reperfusion. Int J Mol Sci. 2023;24: pubmed publisher
Toffali L, D Ulivo B, Giagulli C, Montresor A, Zenaro E, Delledonne M, et al. An isoform of the giant protein titin is a master regulator of human T lymphocyte trafficking. Cell Rep. 2023;42:112516 pubmed publisher
Jing R, Scarfò I, Najia M, Lummertz da Rocha E, Han A, Sanborn M, et al. EZH1 repression generates mature iPSC-derived CAR T cells with enhanced antitumor activity. Cell Stem Cell. 2022;29:1181-1196.e6 pubmed publisher
Mastrogiovanni M, Vargas P, Rose T, Cuche C, Esposito E, Juzans M, et al. The tumor suppressor adenomatous polyposis coli regulates T lymphocyte migration. Sci Adv. 2022;8:eabl5942 pubmed publisher
Schmid M, Kang S, Chen H, Paradise M, Ghebremedhin A, Kaneda M, et al. PI3Kγ stimulates a high molecular weight form of myosin light chain kinase to promote myeloid cell adhesion and tumor inflammation. Nat Commun. 2022;13:1768 pubmed publisher
Lian Z, Saeed A, Peng X, Perrard X, Jia X, Hussain A, et al. Monocyte phenotyping and management of lipoprotein X syndrome. J Clin Lipidol. 2020;14:850-858 pubmed publisher
Natoni A, Farrell M, Harris S, Falank C, Kirkham McCarthy L, Macauley M, et al. Sialyltransferase inhibition leads to inhibition of tumor cell interactions with E-selectin, VCAM1, and MADCAM1, and improves survival in a human multiple myeloma mouse model. Haematologica. 2019;: pubmed publisher
Karpova D, Rettig M, Ritchey J, Cancilla D, Christ S, Gehrs L, et al. Targeting VLA4 integrin and CXCR2 mobilizes serially repopulating hematopoietic stem cells. J Clin Invest. 2019;129:2745-2759 pubmed publisher
Laufer J, Lyck R, Legler D. ZAP70 expression enhances chemokine-driven chronic lymphocytic leukemia cell migration and arrest by valency regulation of integrins. FASEB J. 2018;32:4824-4835 pubmed publisher
Petkau G, Kawano Y, Wolf I, Knoll M, Melchers F. MiR221 promotes precursor B-cell retention in the bone marrow by amplifying the PI3K-signaling pathway in mice. Eur J Immunol. 2018;48:975-989 pubmed publisher
Stewart Hutchinson P, Szasz T, Jaeger E, Onken M, Cooper J, Morley S. Technical Advance: New in vitro method for assaying the migration of primary B cells using an endothelial monolayer as substrate. J Leukoc Biol. 2017;102:941-948 pubmed publisher
Moslem M, Eggenschwiler R, Wichmann C, Buhmann R, Cantz T, Henschler R. Kindlin-2 Modulates the Survival, Differentiation, and Migration of Induced Pluripotent Cell-Derived Mesenchymal Stromal Cells. Stem Cells Int. 2017;2017:7316354 pubmed publisher
Koutsogiannaki S, Schaefers M, Okuno T, Ohba M, Yokomizo T, Priebe G, et al. From the Cover: Prolonged Exposure to Volatile Anesthetic Isoflurane Worsens the Outcome of Polymicrobial Abdominal Sepsis. Toxicol Sci. 2017;156:402-411 pubmed publisher
Ta D, Guedens W, Vranken T, Vanschoenbeek K, Steen Redeker E, Michiels L, et al. Enhanced Biosensor Platforms for Detecting the Atherosclerotic Biomarker VCAM1 Based on Bioconjugation with Uniformly Oriented VCAM1-Targeting Nanobodies. Biosensors (Basel). 2016;6: pubmed publisher
Lozano M, Cook A, Bastida J, Paul D, Iruin G, Cid A, et al. Novel mutations in RASGRP2, which encodes CalDAG-GEFI, abrogate Rap1 activation, causing platelet dysfunction. Blood. 2016;128:1282-9 pubmed publisher
Mukovozov I, Huang Y, Zhang Q, Liu G, Siu A, Sokolskyy Y, et al. The Neurorepellent Slit2 Inhibits Postadhesion Stabilization of Monocytes Tethered to Vascular Endothelial Cells. J Immunol. 2015;195:3334-44 pubmed publisher
Chakraborty S, Hu S, Wu S, Karmenyan A, Chiou A. The interaction affinity between vascular cell adhesion molecule-1 (VCAM-1) and very late antigen-4 (VLA-4) analyzed by quantitative FRET. PLoS ONE. 2015;10:e0121399 pubmed publisher
Mahadev V, Starr R, Wright S, Martinez C, Jensen M, Barish M, et al. Cytokine induction of VCAM-1 but not IL13R?2 on glioma cells: a tale of two antibodies. PLoS ONE. 2014;9:e95123 pubmed publisher
Chaar V, Laurance S, Lapoumeroulie C, Cochet S, De Grandis M, Colin Y, et al. Hydroxycarbamide decreases sickle reticulocyte adhesion to resting endothelium by inhibiting endothelial lutheran/basal cell adhesion molecule (Lu/BCAM) through phosphodiesterase 4A activation. J Biol Chem. 2014;289:11512-21 pubmed publisher
Huang J, Filipe A, Rahuel C, Bonnin P, Mesnard L, Guérin C, et al. Lutheran/basal cell adhesion molecule accelerates progression of crescentic glomerulonephritis in mice. Kidney Int. 2014;85:1123-36 pubmed publisher
Lee J, Sohn J, Ryu S, Hong C, Moon K, Park J. A novel human anti-VCAM-1 monoclonal antibody ameliorates airway inflammation and remodelling. J Cell Mol Med. 2013;17:1271-81 pubmed publisher
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product information

brand :

R&D Systems

master code :

862-VC

SKU :

862-VC-100

product name :

Recombinant Human VCAM-1/CD106 Fc Chimera Protein, CF

unit size :

100 ug

seo description :

The Recombinant Human VCAM-1/CD106 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human VCAM-1/CD106 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

VCAM-1/CD106

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

115-130 kDa, reducing conditions

theoretical molecular weight :

101.6 kDa (monomer)

gene symbol :

VCAM1

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of U937 human histiocytic lymphoma cells. When 5 x 104 cells/well are added to human VCAM-1 coated plates (10 ╡g/mL with 100 ╡L/well), approximately 90-100% will adhere after 1 hour incubation at RT. Optimal dilutions should be determined by each laboratory for each application.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P19320

applications :

Bioactivity

source :

NS0-derived Recombinant Human VCAM-1/CD106 Fc Chimera Protein, CF

USD :

425 USD

alt names :

CD106, CD106 antigen, DKFZp779G2333, INCAM-100, L1CAM, MGC99561, vascular cell adhesion molecule 1, vascular cell adhesion protein 1, V-CAM 1, VCAM1, VCAM-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 week, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage