This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human P-Cadherin Fc Chimera Protein, CF
catalog :
861-PC
quantity :
100 ug
price :
379 USD
citations: 2
Reference
Parnaud G, Lavallard V, Bédat B, Matthey Doret D, Morel P, Berney T, et al. Cadherin engagement improves insulin secretion of single human β-cells. Diabetes. 2015;64:887-96 pubmed publisher
Dunne E, Spring C, Reheman A, Jin W, Berndt M, Newman D, et al. Cadherin 6 has a functional role in platelet aggregation and thrombus formation. Arterioscler Thromb Vasc Biol. 2012;32:1724-31 pubmed publisher
product information
brand :
R&D Systems
master code :
861-PC
SKU :
861-PC-100
product name :
Recombinant Human P-Cadherin Fc Chimera Protein, CF
description :
The Recombinant Human P-Cadherin Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human P-Cadherin Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
P-Cadherin
category :
Proteins and Enzymes
unit size :
100 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
120-130 kDa, under reducing conditions
theoretical molecular weight :
87.4 kDa
gene symbol :
CDH3
details of functionality :
Measured by the ability of the immobilized protein to support the adhesion of A431 human epithelial carcinoma cells. When 1 x 105 cells/well are added to rhP-CAD/Fc Chimera coated plates (10 µg/mL with 100 µL/well), approximately 30-60% will adhere after 1.5 hours at 37° C. Optimal concentration depends on cell type as well as the application or research objectives.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
catalog number base :
861-PC
accessionNumbers :
CAA45177
applications :
Bioactivity
source :
Mouse myeloma cell line, NS0-derived human P-Cadherin protein Human P-Cadherin (Asp108 - Gly654) Accession # CAA45177 IEGRMD Human IgG1 (Pro100 - Lys330) 6-His tag N-terminus C-terminus
2020 USD :
359
2021 USD :
379 USD
alt names :
CAD3, cadherin 3, P-cadherin (placental), cadherin 3, type 1, P-cadherin (placental), cadherin-3, CDH3, CDHP, CDHPcalcium-dependent adhesion protein, placental, HJMD, PCAD, PCadherin, PCADP-cadherin, Placental cadherin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.