Recombinant Cynomolgus PD-1 Fc Chimera Protein, CF | R&D Systems 8578-PD-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Cynomolgus PD-1 Fc Chimera Protein, CF

catalog :

8578-PD-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 1

Reference
Edwards C, Sette A, Cox C, Di Fiore B, Wyre C, Sydoruk D, et al. The multi-specific VH-based Humabody CB213 co-targets PD1 and LAG3 on T cells to promote anti-tumour activity. Br J Cancer. 2021;: pubmed publisher

product information

master code :

8578-PD

SKU :

8578-PD-050

product name :

Recombinant Cynomolgus PD-1 Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Cynomolgus PD-1 Fc Chimera Protein, CF from R&D Systems is derived from HEK293. The Recombinant Cynomolgus PD-1 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

PD-1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE with silver staining.

species :

Cynomolgus Monkey

observed molecular weight :

57-68 kDa, reducing conditions

theoretical molecular weight :

43 kDa (monomer)

gene symbol :

PDCD1

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human PD-L2/B7-DC Fc Chimera (Catalog # 1224-PL ) is coated at 0.25 ╡g/mL (100 ╡L/well), the concentration of Recombinant Cynomolgus Monkey PD-1 Fc Chimera that produces 50% optimal binding response is 0.03-0.15 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_001271065

applications :

Bioactivity

source long :

Human embryonic kidney cell, HEK293-derived cynomolgus monkey PD-1 protein Cynomolgus Monkey PD-1 (Leu25-Gln167) Accession # NP_001271065 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

source short :

HEK293

USD :

432 USD

alt names :

CD279, CD279 antigen, hPD-1, PD1, PD1hPD-l, PDCD1, programmed cell death 1, programmed cell death protein 1, Protein PD-1, SLEB2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage