Recombinant Cynomolgus PD-1 His-tag Protein, CF | R&D Systems 8509-PD-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Cynomolgus PD-1 His-tag Protein, CF

catalog :

8509-PD-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 1

Reference
Issafras H, Fan S, Tseng C, Cheng Y, Lin P, Xiao L, et al. Structural basis of HLX10 PD-1 receptor recognition, a promising anti-PD-1 antibody clinical candidate for cancer immunotherapy. PLoS ONE. 2021;16:e0257972 pubmed publisher

product information

master code :

8509-PD

SKU :

8509-PD-050

product name :

Recombinant Cynomolgus PD-1 His-tag Protein, CF

unit size :

50 ug

description :

The Recombinant Cynomolgus PD-1 His-tag Protein, CF from R&D Systems is derived from HEK293. The Recombinant Cynomolgus PD-1 His-tag Protein, CF has been validated for the following applications: Bioactivity.

target :

PD-1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in sterile PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Cynomolgus Monkey

observed molecular weight :

29-43 kDa, reducing conditions

theoretical molecular weight :

17 kDa

gene symbol :

PDCD1

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human PD-L2/B7-DC Fc Chimera (Catalog # 1224-PL ) is coated at 0.5 ╡g/mL (100 ╡L/well), the concentration of Recombinant Cynomolgus Monkey PD-1, in the presence of Ms x Poly His, that produces 50% optimal binding response is typically 0.3-1.5 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_001271065.1

applications :

Bioactivity

source long :

Human embryonic kidney cell, HEK293-derived cynomolgus monkey PD-1 protein Leu25-Gln167, with a C-terminal 6-His tag

source short :

HEK293

USD :

432 USD

alt names :

CD279, CD279 antigen, hPD-1, PD1, PD1hPD-l, PDCD1, programmed cell death 1, programmed cell death protein 1, Protein PD-1, SLEB2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage