Recombinant Human E-Cadherin Protein, CF | R&D Systems 8505-EC-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human E-Cadherin Protein, CF

catalog :

8505-EC-050

quantity :

50 ug

price :

336 USD

more info or order :

R&D Systems product webpage

citations: 9

Reference
Carriqu xed Madro xf1 al B, Sheldon J, Duven M, Stegmann C, Cirksena K, Wyler E, et al. The matrix metalloproteinase ADAM10 supports hepatitis C virus entry and cell-to-cell spread via its sheddase activity. PLoS Pathog. 2023;19:e1011759 pubmed publisher
Souralova T, Hulinova D, Jeseta M, Ventruba P, Hampl A, Koutna I. Truncated vitronectin with E-cadherin enables the xeno-free derivation of human embryonic stem cells. Sci Rep. 2023;13:15062 pubmed publisher
Zhang X, Lin Y, Xu X, Wen S, Wang Z, Gu J, et al. HtrA is involved in stress response and adhesion in Glaesserella parasuis serovar 5 strain Nagasaki. Vet Microbiol. 2023;282:109748 pubmed publisher
Ceschin I, Ceschin A, Joya M, Mitsugi T, Nishikawa L, Krepischi A, et al. Functional assessment of donated human embryos for the generation of pluripotent embryonic stem cell lines. Reprod Biomed Online. 2023;46:491-501 pubmed publisher
Kwak M, Southard K, Kim W, Lin A, Kim N, Gopalappa R, et al. Adherens junctions organize size-selective proteolytic hotspots critical for Notch signalling. Nat Cell Biol. 2022;24:1739-1753 pubmed publisher
Micalizzi D, Che D, Nicholson B, Edd J, Desai N, Lang E, et al. Targeting breast and pancreatic cancer metastasis using a dual-cadherin antibody. Proc Natl Acad Sci U S A. 2022;119:e2209563119 pubmed publisher
Tabdanov E, Puram V, Win Z, Alamgir A, Alford P, Provenzano P. Bimodal sensing of guidance cues in mechanically distinct microenvironments. Nat Commun. 2018;9:4891 pubmed publisher
Yamada M, Takahashi N, Matsuda Y, Sato K, Yokoji M, Sulijaya B, et al. A bacterial metabolite ameliorates periodontal pathogen-induced gingival epithelial barrier disruption via GPR40 signaling. Sci Rep. 2018;8:9008 pubmed publisher
Caldwell J, Collins M, Kemme K, Sherrill J, Wen T, Rochman M, et al. Cadherin 26 is an alpha integrin-binding epithelial receptor regulated during allergic inflammation. Mucosal Immunol. 2017;10:1190-1201 pubmed publisher

product information

brand :

R&D Systems

master code :

8505-EC

SKU :

8505-EC-050

product name :

Recombinant Human E-Cadherin Protein, CF

unit size :

50 ug

seo description :

The Recombinant Human E-Cadherin Protein, CF from R&D Systems is derived from HEK293. The Recombinant Human E-Cadherin Protein, CF has been validated for the following applications: Bioactivity.

target :

E-Cadherin

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE with silver staining

species :

Human

observed molecular weight :

74-92 kDa, reducing conditions

theoretical molecular weight :

61 kDa

gene symbol :

CDH1

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of the MCF-7 human breast cancer cells. The ED50 for this effect is 0.2-1 ╡g/mL

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P12830

applications :

Bioactivity

source :

HEK293-derived Recombinant Human E-Cadherin Protein, CF

USD :

336 USD

alt names :

Arc-1, CAD1, cadherin 1, E-cadherin (epithelial), cadherin 1, type 1, E-cadherin (epithelial), cadherin-1, calcium-dependent adhesion protein, epithelial, CAM 120/80, CD324, CD324 antigen, CDH1, CDHE, cell-CAM 120/80, Cell-CAM120/80, ECAD, E-cadherin, ECadherin, Epithelial cadherin, LCAM, L-CAM, UVOE-Cadherin, uvomorulin

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage