product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Oncostatin M (HEK-293-expressed) Protein
catalog :
8475-OM-010
quantity :
10 ug (also 50 ug, 1 mg)
price :
252 USD
more info or order :
R&D Systems product webpage
citations: 4
Reference
Zhou Y, Stevis P, Cao J, Ehrlich G, Jones J, Rafique A, et al. Structures of complete extracellular assemblies of type I and type II Oncostatin M receptor complexes. Nat Commun. 2024;15:9776 pubmed publisher
Zhang C, Zhang Q, Chen J, Li H, Cheng F, Wang Y, et al. Neutrophils in nasal polyps exhibit transcriptional adaptation and proinflammatory roles that depend on local polyp milieu. JCI Insight. 2024;9: pubmed publisher
Kleuskens M, Bek M, Al Halabi Y, Blokhuis B, Diks M, Haasnoot M, et al. Mast cells disrupt the function of the esophageal epithelial barrier. Mucosal Immunol. 2023;16:567-577 pubmed publisher
Parafati M, Kirby R, Khorasanizadeh S, Rastinejad F, Malany S. A nonalcoholic fatty liver disease model in human induced pluripotent stem cell-derived hepatocytes, created by endoplasmic reticulum stress-induced steatosis. Dis Model Mech. 2018;11: pubmed publisher
product information
brand :
R&D Systems
catalog number base :
8475-OM
SKU :
8475-OM-010
product name :
Recombinant Human Oncostatin M (HEK-293-expressed) Protein
units size :
10 ug (also 50 ug, 1 mg)
description :
The Recombinant Human Oncostatin M (HEK-293-expressed) Protein from R&D Systems is derived from HEK293. The Recombinant Human Oncostatin M (HEK-293-expressed) Protein has been validated for the following applications: Bioactivity.
target :
Oncostatin M/OSM
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
all_available conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE with silver staining
species :
Human
observed molecular weight :
27-35 kDa, reducing conditions
theoretical molecular weight :
22 kDa
gene symbol :
OSM
details of functionality :
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. Kitamura, T. et al . (1989) J. Cell Physiol. 140 :323. The ED50 for this effect is 0.05-0.3 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P13725
applications :
Bioactivity
source :
HEK293-derived Recombinant Human Oncostatin M (HEK-293-expressed) Protein
USD :
252 USD
alt names :
MGC20461, oncostatin M, oncostatin-M
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.