This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human PTEN Protein, CF
catalog :
847-PN
quantity :
10 ug
price :
339 USD
citations: 2
Reference
Chen M, Nowak D, Narula N, Robinson B, Watrud K, Ambrico A, et al. The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein. J Cell Biol. 2017;216:641-656 pubmed publisher
Song P, Xie Z, Wu Y, Xu J, Dong Y, Zou M. Protein kinase Czeta-dependent LKB1 serine 428 phosphorylation increases LKB1 nucleus export and apoptosis in endothelial cells. J Biol Chem. 2008;283:12446-55 pubmed publisher
product information
brand :
R&D Systems
master code :
847-PN
SKU :
847-PN-010
product name :
Recombinant Human PTEN Protein, CF
description :
The Recombinant Human PTEN Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human PTEN Protein, CF has been validated for the following applications: Inhibition Activity.
target :
PTEN
category :
Proteins and Enzymes
unit size :
10 ug
buffer :
Supplied as a 0.2 µm filtered solution in HEPES, NaCl, EDTA, Glycerol and Betamercaptoethanol.
conjugate :
Unconjugated
purity :
>80%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
59 kDa, reducing conditions
theoretical molecular weight :
48 kDa
gene symbol :
PTEN
details of functionality :
Measured by its ability to dephosphorylate either diC8PIP3 or diC16PIP3. The specific activity is 480 nmol/min/mg, as measured under the described conditions.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
catalog number base :
847-PN
accessionNumbers :
P60484
applications :
Inhibition Activity
source :
E. coli -derived human PTEN protein Thr2-Val403, with a C-terminal 6-His tag
2020 USD :
339
2021 USD :
339 USD
alt names :
BZS, EC 3.1.3.16,10q23del, EC 3.1.3.48, EC 3.1.3.67, GLM2, MMAC1, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, MMAC1MGC11227, Mutated in multiple advanced cancers 1, phosphatase and tensin homologDEC, phosphatidylinositol-34,5-trisphosphate 3-phosphatase and dual-specificityprotein phosphatase PTEN, PTEN1, TEP1MHAM
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 °C as supplied. 3 months, -70 °C under sterile conditions after opening.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.