Recombinant Human PTEN Protein, CF | R&D Systems 847-PN-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human PTEN Protein, CF

catalog :

847-PN-010

quantity :

10 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Chang T, Chu P, Lin H, Huang K, Hung W, Shan Y, et al. PTEN regulates invasiveness in pancreatic neuroendocrine tumors through DUSP19-mediated VEGFR3 dephosphorylation. J Biomed Sci. 2022;29:92 pubmed publisher
Chen M, Nowak D, Narula N, Robinson B, Watrud K, Ambrico A, et al. The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein. J Cell Biol. 2017;216:641-656 pubmed publisher
Song P, Xie Z, Wu Y, Xu J, Dong Y, Zou M. Protein kinase Czeta-dependent LKB1 serine 428 phosphorylation increases LKB1 nucleus export and apoptosis in endothelial cells. J Biol Chem. 2008;283:12446-55 pubmed publisher

product information

master code :

847-PN

SKU :

847-PN-010

product name :

Recombinant Human PTEN Protein, CF

unit size :

10 ug

description :

The Recombinant Human PTEN Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human PTEN Protein, CF has been validated for the following applications: Inhibition Activity.

target :

PTEN

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in HEPES, NaCl, EDTA, Glycerol and Betamercaptoethanol.

conjugate :

Unconjugated

purity :

>80%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

59 kDa, reducing conditions

theoretical molecular weight :

48 kDa

gene symbol :

PTEN

details of functionality :

Measured by its ability to dephosphorylate either diC8PIP3 or diC16PIP3. The specific activity is 480 nmol/min/mg, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P60484

applications :

Inhibition Activity

source long :

E. coli -derived human PTEN protein Thr2-Val403, with a C-terminal 6-His tag

source short :

E. coli

USD :

432 USD

alt names :

BZS, EC 3.1.3.16,10q23del, EC 3.1.3.48, EC 3.1.3.67, GLM2, MMAC1, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, MMAC1MGC11227, Mutated in multiple advanced cancers 1, phosphatase and tensin homologDEC, phosphatidylinositol-34,5-trisphosphate 3-phosphatase and dual-specificityprotein phosphatase PTEN, PTEN1, TEP1MHAM

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 ░C as supplied. 3 months, -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage