Recombinant Mouse CCL1/TCA-3 Protein | R&D Systems 845-TC-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse CCL1/TCA-3 Protein

catalog :

845-TC-025

quantity :

25 ug

price :

417 USD

more info or order :

R&D Systems product webpage

citations: 8

Reference
Haque N, Tuteja A, Haque N. CC chemokine CCL1 receptor CCR8 mediates conversion of mesenchymal stem cells to embryoid bodies expressing FOXP3+CCR8+ regulatory T cells. PLoS ONE. 2019;14:e0218944 pubmed publisher
Xu Y, Dong X, Qi P, Ye Y, Shen W, Leng L, et al. Sox2 Communicates With Tregs Through CCL1 To Promote The Stemness Property Of Breast Cancer Cells. Stem Cells. 2017;: pubmed publisher
Geherin S, GÃ³mez D, Glabman R, Ruthel G, Hamann A, Debes G. IL-10+ Innate-like B Cells Are Part of the Skin Immune System and Require Î±4Î²1 Integrin To Migrate between the Peritoneum and Inflamed Skin. J Immunol. 2016;196:2514-2525 pubmed publisher
Wu Z, MacNeil A, Junkins R, Li B, Berman J, Lin T. Mast cell Fc?RI-induced early growth response 2 regulates CC chemokine ligand 1-dependent CD4+ T cell migration. J Immunol. 2013;190:4500-7 pubmed publisher
Islam S, Chang D, Colvin R, Byrne M, McCully M, Moser B, et al. Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells. Nat Immunol. 2011;12:167-77 pubmed publisher
Kearley J, Buckland K, Mathie S, Lloyd C. Resolution of allergic inflammation and airway hyperreactivity is dependent upon disruption of the T1/ST2-IL-33 pathway. Am J Respir Crit Care Med. 2009;179:772-81 pubmed publisher
Kearley J, Robinson D, Lloyd C. CD4+CD25+ regulatory T cells reverse established allergic airway inflammation and prevent airway remodeling. J Allergy Clin Immunol. 2008;122:617-24.e6 pubmed publisher
Najarro P, Lee H, Fox J, Pease J, Smith G. Yaba-like disease virus protein 7L is a cell-surface receptor for chemokine CCL1. J Gen Virol. 2003;84:3325-36 pubmed

product information

brand :

R&D Systems

master code :

845-TC

SKU :

845-TC-025

product name :

Recombinant Mouse CCL1/TCA-3 Protein

description :

The Recombinant Mouse CCL1/TCA-3 Protein from R&D Systems is derived from NS0. The Recombinant Mouse CCL1/TCA-3 Protein has been validated for the following applications: Bioactivity.

target :

CCL1/I-309/TCA-3

category :

Proteins and Enzymes

unit sizes :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

13-16 kDa, reducing conditions

theoretical molecular weight :

7.8 kDa

gene symbol :

Ccl1

details of functionality :

Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with mouse CCR8. The ED50 for this effect is 0.5-2.0 ng/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P10146

applications :

Bioactivity

source :

NS0-derived Recombinant Mouse CCL1/TCA-3 Protein

USD :

417 USD

alt names :

C-C motif chemokine 1, chemokine (C-C motif) ligand 1, I-309, inflammatory cytokine I-309, P500, SCYA1, SCYA1Small-inducible cytokine A1, SCYA2, SISe, small inducible cytokine A1 (I-309, homologous to mouse Tca-3), T lymphocyte-secreted protein I-309, TCA3, TCA-3

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage