Recombinant Mouse DCC Fc Chimera Protein, CF | R&D Systems 844-DC-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse DCC Fc Chimera Protein, CF

catalog :

844-DC-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Brunet I, Gordon E, Han J, Cristofaro B, Broqueres You D, Liu C, et al. Netrin-1 controls sympathetic arterial innervation. J Clin Invest. 2014;124:3230-40 pubmed publisher
Mille F, Llambi F, Guix C, Delloye Bourgeois C, Guenebeaud C, Castro Obregon S, et al. Interfering with multimerization of netrin-1 receptors triggers tumor cell death. Cell Death Differ. 2009;16:1344-51 pubmed publisher

product information

master code :

844-DC

SKU :

844-DC-050

product name :

Recombinant Mouse DCC Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse DCC Fc Chimera Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Mouse DCC Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.

target :

DCC

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

160-170 kDa, reducing conditions

theoretical molecular weight :

146 kDa (monomer)

gene symbol :

Dcc

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized rmDCC/Fc Chimera at 2 ╡g/mL (100 ╡L/well) can bind rcNetrin-1 with a linear range of 6-400áng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P70211

applications :

Binding Activity

source long :

Spodoptera frugiperda , Sf 21 (baculovirus)-derived mouse DCC protein Mouse DCC (Phe32 - Asn1097) Accession # P70211 DIEGRMD Human IgG1 (Pro100 - Lys330) 6-His tag N-terminus C-terminus

source short :

Sf 21 (baculovirus)

USD :

432 USD

alt names :

Colorectal cancer suppressor, CRC18, CRCR1, deleted in colorectal cancer protein, deleted in colorectal carcinoma, IGDCC1colorectal tumor suppressor, Immunoglobulin superfamily DCC subclass member 1, immunoglobulin superfamily, DCC subclass, member 1, netrin receptor DCC, Tumor suppressor protein DCC

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage