Recombinant Human IL-28A/IFN-lambda 2 (HEK293) Protein | R&D Systems 8417-IL-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IL-28A/IFN-lambda 2 (HEK293) Protein

catalog :

8417-IL-025

quantity :

25 ug

price :

400 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Groen K, Kuratli R, Sar L, Vasou A, Huber M, Hughes D, et al. Highly sensitive reporter cell line for detection of interferon types I-III and their neutralization by antibodies. Eur J Immunol. 2024;54:e2451325 pubmed publisher
Song J, Chow R, Pe xf1 a Hern xe1 ndez M, Zhang L, Loeb S, So E, et al. LRRC15 inhibits SARS-CoV-2 cellular entry in trans. PLoS Biol. 2022;20:e3001805 pubmed publisher
Chung J, Hong S, Seo N, Kim T, An H, Lee P, et al. Structure-based glycoengineering of interferon lambda 4 enhances its productivity and anti-viral potency. Cytokine. 2020;125:154833 pubmed publisher
Obajemu A, Rao N, Dilley K, Vargas J, Sheikh F, Donnelly R, et al. IFN-Î»4 Attenuates Antiviral Responses by Enhancing Negative Regulation of IFN Signaling. J Immunol. 2017;199:3808-3820 pubmed publisher

product information

master code :

8417-IL

SKU :

8417-IL-025

product name :

Recombinant Human IL-28A/IFN-lambda 2 (HEK293) Protein

unit size :

25 ug

description :

The Recombinant Human IL-28A/IFN-lambda 2 (HEK293) Protein from R&D Systems is derived from HEK293. The Recombinant Human IL-28A/IFN-lambda 2 (HEK293) Protein has been validated for the following applications: Bioactivity.

target :

IL-28A/IFN-lambda 2

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE with silver staining

species :

Human

observed molecular weight :

20-23 kDa, reducing condtions

theoretical molecular weight :

20 kDa

gene symbol :

IFNL2

details of functionality :

Measured in an anti-viral assay using HepG2 human hepatocellular carcinoma cells infected with encephalomyocarditis (EMC) virus. Sheppard, P. et al . (2003) Nat. Immunol. 4 :63. The ED50 for this effect is 5-25 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q8IZJ0

applications :

Bioactivity

source long :

Human embryonic kidney cell, HEK293-derived human IL-28A/IFN-lambda 2 protein Val26-Val200

source short :

HEK293

USD :

400 USD

alt names :

interleukin-28A, IFN-lambda 2, IL28A, IL-28A, interferon, lambda 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage