product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human IL-28A/IFN-lambda 2 (HEK293) Protein
catalog :
8417-IL-025
quantity :
25 ug
price :
400 USD
more info or order :
R&D Systems product webpage
citations: 4
Reference
Groen K, Kuratli R, Sar L, Vasou A, Huber M, Hughes D, et al. Highly sensitive reporter cell line for detection of interferon types I-III and their neutralization by antibodies. Eur J Immunol. 2024;54:e2451325 pubmed publisher
Song J, Chow R, Pe xf1 a Hern xe1 ndez M, Zhang L, Loeb S, So E, et al. LRRC15 inhibits SARS-CoV-2 cellular entry in trans. PLoS Biol. 2022;20:e3001805 pubmed publisher
Chung J, Hong S, Seo N, Kim T, An H, Lee P, et al. Structure-based glycoengineering of interferon lambda 4 enhances its productivity and anti-viral potency. Cytokine. 2020;125:154833 pubmed publisher
Obajemu A, Rao N, Dilley K, Vargas J, Sheikh F, Donnelly R, et al. IFN-λ4 Attenuates Antiviral Responses by Enhancing Negative Regulation of IFN Signaling. J Immunol. 2017;199:3808-3820 pubmed publisher
product information
brand :
R&D Systems
catalog number base :
8417-IL
SKU :
8417-IL-025
product name :
Recombinant Human IL-28A/IFN-lambda 2 (HEK293) Protein
units size :
25 ug
description :
The Recombinant Human IL-28A/IFN-lambda 2 (HEK293) Protein from R&D Systems is derived from HEK293. The Recombinant Human IL-28A/IFN-lambda 2 (HEK293) Protein has been validated for the following applications: Bioactivity.
target :
IL-28A/IFN-lambda 2
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
all_available conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE with silver staining
species :
Human
observed molecular weight :
20-23 kDa, reducing condtions
theoretical molecular weight :
20 kDa
gene symbol :
IFNL2
details of functionality :
Measured in an anti-viral assay using HepG2 human hepatocellular carcinoma cells infected with encephalomyocarditis (EMC) virus. Sheppard, P. et al . (2003) Nat. Immunol. 4 :63. The ED50 for this effect is 5-25 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q8IZJ0
applications :
Bioactivity
source :
HEK293-derived Recombinant Human IL-28A/IFN-lambda 2 (HEK293) Protein
USD :
400 USD
alt names :
interleukin-28A, IFN-lambda 2, IL28A, IL-28A, interferon, lambda 2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.