Recombinant Human IL-12 R beta 1 Fc Chimera Protein, CF | R&D Systems 839-B1-100 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IL-12 R beta 1 Fc Chimera Protein, CF

catalog :

839-B1-100

quantity :

100 ug

price :

394 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Roberts K, Cubitt M, Carlton T, Rodrigues Duarte L, Maggiore L, Chai R, et al. Preclinical development of a bispecific TNFα/IL-23 neutralising domain antibody as a novel oral treatment for inflammatory bowel disease. Sci Rep. 2021;11:19422 pubmed publisher
Yu R, Gallagher G. A naturally occurring, soluble antagonist of human IL-23 inhibits the development and in vitro function of human Th17 cells. J Immunol. 2010;185:7302-8 pubmed publisher

product information

brand :

R&D Systems

master code :

839-B1

SKU :

839-B1-100

product name :

Recombinant Human IL-12 R beta 1 Fc Chimera Protein, CF

description :

The Recombinant Human IL-12 R beta 1 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human IL-12 R beta 1 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.

target :

IL-12 R beta 1

category :

Proteins and Enzymes

unit sizes :

100 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

110 kDa, reducing conditions

theoretical molecular weight :

84.5 kDa (monomer)

gene symbol :

IL12RB1

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized rhIL-12 R beta 1/Fc Chimera at 5 µg/mL (100 µL/well) can bind rhIL-12 with a linear range of 0.78-50 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P42701

applications :

Binding Activity

source :

NS0-derived Recombinant Human IL-12 R beta 1 Fc Chimera Protein, CF

USD :

394 USD

alt names :

CD212, CD212 antigen, IL-12 receptor beta component, IL-12 receptor subunit beta-1, IL12R, IL12R beta 1, IL-12R subunit beta-1, IL12RB, IL12RB1, IL-12RB1, IL-12R-beta-1, IL-12R-BETA1, interleukin 12 receptor, beta 1, interleukin-12 receptor beta-1 chain, interleukin-12 receptor subunit beta-1, MGC34454

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage