Recombinant Human GDF-7 Protein, CF | R&D Systems 8386-G7-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human GDF-7 Protein, CF

catalog :

8386-G7-050

quantity :

50 ug

price :

400 USD

citations: 5

Reference
Dave B, Chen X, McCready F, Charton C, Morley R, Tailor J, et al. Directed differentiation of human hindbrain neuroepithelial stem cells recapitulates cerebellar granule neurogenesis. Development. 2023;150: pubmed publisher
Oliva R, Núñez I, Segunda M, Peralta O. Tenogenic Potential of Equine Fetal Mesenchymal Stem Cells Under The In Vitro Effect of Bone Morphogenetic Protein-12 (BMP-12). J Equine Vet Sci. 2021;104:103681 pubmed publisher
Huang M, Tailor J, Zhen Q, Gillmor A, Miller M, Weishaupt H, et al. Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis. Cell Stem Cell. 2019;: pubmed publisher
Izumi S, Otsuru S, Adachi N, Akabudike N, Enomoto Iwamoto M. Control of glucose metabolism is important in tenogenic differentiation of progenitors derived from human injured tendons. PLoS ONE. 2019;14:e0213912 pubmed publisher
Roth S, Schubert S, Scheibe P, Groß C, Brehm W, Burk J. Growth Factor-Mediated Tenogenic Induction of Multipotent Mesenchymal Stromal Cells Is Altered by the Microenvironment of Tendon Matrix. Cell Transplant. 2018;27:1434-1450 pubmed publisher

product information

master code :

8386-G7

SKU :

8386-G7-050

product name :

Recombinant Human GDF-7 Protein, CF

unit size :

50 ug

description :

The Recombinant Human GDF-7 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human GDF-7 Protein, CF has been validated for the following applications: Bioactivity.

target :

GDF-7/BMP-12

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in HCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE with silver staining.

species :

Human

observed molecular weight :

14 kDa, reducing conditions

theoretical molecular weight :

14 kDa

gene symbol :

GDF7

details of functionality :

Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Nakamura, K. et al . (1999) Exp. Cell Res. 250 :351. The ED50 for this effect is typically 0.25-1.25 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

top caption :

GDF-7-induced Alkaline Phosphatase Production.

accessionNumbers :

Q7Z4P5

applications :

Bioactivity

source long :

E. coli -derived human GDF-7/BMP-12 protein Thr322-Arg450

source short :

E. coli

USD :

400 USD

alt names :

BMP12, BMP-12, GDF7, GDF-7, growth differentiation factor 7, growth/differentiation factor 7

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.