Recombinant Human GDF-5 Protein, CF | R&D Systems 8340-G5-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human GDF-5 Protein, CF

catalog :

8340-G5-050

quantity :

50 ug

price :

323 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Castro Viñuelas R, Sanjurjo Rodríguez C, Piñeiro Ramil M, Hermida Gómez T, Rodríguez Fernández S, Oreiro N, et al. Generation and characterization of human induced pluripotent stem cells (iPSCs) from hand osteoarthritis patient-derived fibroblasts. Sci Rep. 2020;10:4272 pubmed publisher
Lorda Diez C, Montero J, Choe S, Garcia Porrero J, Hurle J. Ligand- and stage-dependent divergent functions of BMP signaling in the differentiation of embryonic skeletogenic progenitors in vitro. J Bone Miner Res. 2014;29:735-48 pubmed publisher

image

image 1 :

Recombinant Human GDF-5 Protein Bioactivity

product information

brand :

R&D Systems

master code :

8340-G5

SKU :

8340-G5-050

product name :

Recombinant Human GDF-5 Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse Angiopoietin-like 3 (aa 17-220), CF from R&D Systems is derived from CHO. The Recombinant Mouse Angiopoietin-like 3 (aa 17-220), CF has been validated for the following applications: Bioactivity.

target :

GDF-5/BMP-14

category :

Proteins and Enzymes

alt names :

BMP14, BMP-14, Cartilage-derived morphogenetic protein 1, cartilage-derived morphogenetic protein-1, CDMP-1, CDMP1LAP4, GDF5, GDF-5, growth differentiation factor 5, growth/differentiation factor 5, OS5, Radotermin, SYNS2

buffer :

Lyophilized from a 0.2 µm filtered solution in HCl.

conjugate :

Unconjugated

all available conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE with silver staining.

species :

Human

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

observed molecular weight :

14 kDa, reducing conditions

theoretical molecular weight :

14 kDa

gene symbol :

GDF5

details of functionality :

Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Nakamura, K. et al . (1999) Exp. Cell Res. 250 :351. The ED50 for this effect is 0.2-1.2 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P43026

applications :

Bioactivity

source :

E. coli-derived Recombinant Human GDF-5 Protein, CF

USD :

299

Jul-22 :

323 USD

sizes available :

50 ug

more info or order :

R&D Systems product webpage