Recombinant Mouse Gas6 (Full Length) Protein, CF | R&D Systems 8310-GS-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Gas6 (Full Length) Protein, CF

catalog :

8310-GS-050

quantity :

50 ug

price :

509 USD

citations: 5

Reference
Fane M, Chhabra Y, Alicea G, Maranto D, Douglass S, Webster M, et al. Stromal changes in the aged lung induce an emergence from melanoma dormancy. Nature. 2022;606:396-405 pubmed publisher
Salmi L, Gavelli F, Patrucco F, Bellan M, Sainaghi P, Avanzi G, et al. Growth Arrest-Specific Gene 6 Administration Ameliorates Sepsis-Induced Organ Damage in Mice and Reduces ROS Formation In Vitro. Cells. 2021;10: pubmed publisher
Choi S, Zhang B, Ma S, Gonzalez Celeiro M, Stein D, Jin X, et al. Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence. Nature. 2021;592:428-432 pubmed publisher
Nidetz N, Gallagher T, Wiethoff C. Inhibition of type I interferon responses by adenovirus serotype-dependent Gas6 binding. Virology. 2018;515:150-157 pubmed publisher
Zhao G, Zheng J, Bian J, Chen L, Dong N, Yu Y, et al. Growth Arrest-Specific 6 Enhances the Suppressive Function of CD4+CD25+ Regulatory T Cells Mainly through Axl Receptor. Mediators Inflamm. 2017;2017:6848430 pubmed publisher

product information

master code :

8310-GS

SKU :

8310-GS-050

product name :

Recombinant Mouse Gas6 (Full Length) Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse Gas6 (Full Length) Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Gas6 (Full Length) Protein, CF has been validated for the following applications: Binding Activity.

target :

Gas6

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Mouse

observed molecular weight :

78-94 kDa, reducing conditions

theoretical molecular weight :

71 kDa

gene symbol :

Gas6

details of functionality :

Measured by its ability to down regulate the expression of Axl in DU145 human prostate carcinoma cells. Mishra, A. etáal . (2012) Mol. Cancer Res. 10 :703. The ED50 for this effect is 20-100 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Mouse Gas6 (Full Length) Protein Bioactivity

accessionNumbers :

CAA42507

applications :

Binding Activity

source long :

Mouse myeloma cell line, NS0-derived mouse Gas6 protein Ala46-Pro673, with a C-terminal 6-His tag

source short :

NS0

USD :

509 USD

alt names :

AXLLG, AXLLGAXL stimulatory factor, AXSFAXL receptor tyrosine kinase ligand, DKFZp666G247, FLJ34709, GAS-6, growth arrest-specific 6, growth arrest-specific protein 6

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.